关键词:
Anthrax
Bioterrorism
Adolescent
Adult
Aged
Anthrax Vaccines
Anti-Bacterial Agents
Antibiotic Prophylaxis
Bacillus anthracis
Child
Child
Preschool
Decontamination
Environmental Exposure
Female
Gastrointestinal Diseases
History of Medicine
20th Cent.
History of Medicine
21st Cent.
Human
Immunocompromised Host
Infant
Infection Control
Male
Middle Aged
Pregnancy
Respiratory Tract Infections
Skin Diseases
Bacterial
Spores
Bacterial
Support
Non-U.S. Gov't
United States
Vaccination
摘要:
Objective To review and update consensus-based recommendations for medical and public health professionals following a Bacillus anthracis attack against a civilian population. Participants The working group included 23 experts from academic medical centers, research organizations, and governmental, military, public health, and emergency management institutions and agencies. Evidence MEDLINE databases were searched from January 1966 to January 2002, using the Medical Subject Headings anthrax, Bacillus anthracis, biological weapon, biological terrorism, biological warfare, and biowarfare. Reference review identified work published before 1966. Participants identified unpublished sources. Consensus Process The first draft synthesized the gathered information. Written comments were incorporated into subsequent drafts. The final statement incorporated all relevant evidence from the search along with consensus recommendations. Conclusions Specific recommendations include diagnosis of anthrax infection, indications for vaccination, therapy, postexposure prophylaxis, decontamination of the environment, and suggested research. This revised consensus statement presents new information based on the analysis of the anthrax attacks of 2001, including developments in the investigation of the anthrax attacks of 2001;important symptoms, signs, and laboratory studies;new diagnostic clues that may help future recognition of this disease;current anthrax vaccine information;updated antibiotic therapeutic considerations;and judgments about environmental surveillance and decontamination.