关键词： 换向器   转子   损坏   环火  

摘要： 对630E电动轮转子换向器损坏进行分析研究,阐述了对换向器前端绑扎无纬带、更换聚四氟乙烯环、跳片处理、换向器表面检修保养的工艺过程。

关键词： 电力负荷预测   傅里叶级数   BP神经网络   决策支持系统  

摘要： 本文讲述了决策支持系统在电力负荷预测中的应用.分析给定样本的用户历史用电数据,针对预测目标数据量的大小,分别用傅里叶级数和数据挖掘技术中的BP神经网络建立了电力负荷预测分析模型.利用模型为电力系统生产计划提供辅助决策,以缓解供电压力.本研究对决策支持系统和数据挖掘技术的应用有一定的参考价值.

关键词： 流域污染  

ISBN: (纸本)9787517050629

摘要： 本书全面系统介绍了流域水污染防治规划决策的模型方法和应用研究成果。全书共分8章，主要内容包括：概述、流域水环境形势诊断与预警模型、流域水环境压力预测与分析模型、流域水污染物总量目标分配模型、流域水环境质量模拟预测模型、流域城镇污水处理厂建设方案优选评估模型等。

关键词： FLIRE   DSS system   On-line simulation   Fire   Flood   Natural disaster  

摘要： The FLIRE DSS is a web-based Decision Support System for the combined forest and flood risk management and planning. State of the art tools and models have been used in order to enable Civil Protection agencies and local stakeholders to take advantage of web based DSS with no need of local complex infrastructure and maintenance. Civil protection agencies can predict the behavior of a fire event using real time data and in that way to plan its efficient elimination. Also, they can implement "what-if' scenarios for areas prone to fire and thus develop plans for forest fire management. Flood services include flood maps and flood-related warnings;these become available to relevant authorities for visualization and further analysis on a daily basis. Real time weather data from ground stations provide the necessary inputs for the calculation of the fire model in real time and a high resolution weather forecast grid support flood modeling and "what-if' scenarios for the fire modeling. The innovations of the FLIRE DSS are the use of common Earth Observation (EO) data as the backbone of the system to produce data for the support of fire and flood models, the common use of weather related information, the distributed architecture of the system and the web-based access of it with no need for installation of dedicated software. All these can be accessed by all means of computer sources like PC, laptop, Smartphone and tablet either by normal network connection or by using 3G and 4G cellular network. The latter is important for the accessibility of the FLIRE DSS during firefighting or rescue operations during flood events. FLIRE DSS can be easily transferred to other areas with similar characteristics due to its robust architecture and its flexibility. (C) 2016 Elsevier Ltd. All rights reserved.

关键词： 灌区  

ISBN: (纸本)9787227065357

摘要： 本书是关于研究宁夏北干渠灌区多目标优化配水决策支持系统的研究。全书应用大量的数据分析了宁夏北干灌区用水总量及对用水总量控制时, 系统对配水决策的重要作用。多目标优化配水决策支持系统对宁夏节约用水的政策决策具有很高的参考价值。

关键词： prostasin   dextran sodium sulfate   inflammatory bowel disease  

摘要： Background: Inflammatory bowel diseases (IBD) including ulcerative colitis and Crohn's disease are diseases with impaired epithelial barrier function. We aimed to investigate whether mutated prostasin and thus, reduced colonic epithelial sodium channel activity predisposes to develop an experimentally dextran sodium sulfate (DSS)-induced colitis. Methods: Wildtype, heterozygous (fr(CR)/+), and homozygous (fr(CR)/fr(CR)) prostasin-mutant rats were treated 7 days with DSS followed by 7 days of recovery and analyzed with respect to histology, clinicopathological parameters, inflammatory marker mRNA transcript expression, and sodium transporter protein expression. Results: In this study, a more detailed analysis on rat fr(CR)/fr(CR) colons revealed reduced numbers of crypt and goblet cells, and local angiodysplasia, as compared with heterozygous (fr(CR)/+) and wildtype littermates. Following 2% DSS treatment for 7 days followed by 7 days recovery, fr(CR)/fr(CR) animals lost body weight, and reached maximal diarrhea score and highest disease activity after only 3 days, and strongly increased cytokine levels. The histology score significantly increased in all groups, but fr(CR)/fr(CR) colons further displayed pronounced histological alterations with near absence of goblet cells, rearrangement of the lamina propria, and presence of neutrophils, eosinophils, and macrophages. Additionally, fr(CR)/fr(CR) colons showed ulcerations and edemas that were absent in fr(CR)/+ and wildtype littermates. Following recovery, fr(CR)/fr(CR) rats reached, although significantly delayed, near-normal diarrhea score and disease activity, but exhibited severe architectural remodeling, despite unchanged sodium transporter protein expression. Conclusions: In summary, our results demonstrate a protective role of colonic prostasin expression against experimental colitis, and thus represent a susceptibility gene in the development of inflammatory bowel disease.

关键词： "Knowledge House"   DWS   DMS   DSS   TOWS methodologies   railway sector   Dcompetitor analysis  

摘要： In completing a competitors' analysis in the railway sector by using the "Knowledge House" method, there is frequently a problem of data and information accessibility. The quality of primary information has direct influence on the quality of analytical conclusions. One more condition for the qualitative application of this method is the intellectual capital and experience of the analyst. One should note that in this regard we face another problem, that of selection of proper personnel, on the qualification of whom depends the accuracy of the evaluation and final results, on the basis of which strategic decisions are taken. The main aim of the paper is to assess the opportunities for applications of competitive intelligence methods in the railway sector. The study is using "Knowledge House", DWS, DMS, DSS methodologies. Having analysed the scientific works the direct scientific sources of information, which are oriented to the application of the methods of competitive intelligence to the railway sector, have not been identified. The paper is absolutely original in that until now the competitive intelligence techniques have not been applied for the railway sector companies. Considering the fact that foreign companies, which compete for freighting at the international level, are regarded as the main competitors of the railway sector, the use of the methods of the competitive intelligence becomes more important while fighting for the part of the market. The competitive intelligence methods and their application to the railway sector companies are little studied. In accordance with application of the relevant methods in other sectors, it can be assumed that these innovative approaches could have a positive impact on the competitiveness of companies in the railway sector and their income.

关键词： Black tea   colonic inflammation   IFN-gamma   IL-1 beta   inflammatory bowel disease   TNF-alpha  

摘要： Inflammatory bowel disease (IBD) is highly prevalent worldwide and includes ulcerative colitis (UC) and Crohn's disease. It is a high incidence rate disease all over the world and an inducement of colon cancer. The aim of this study was to investigate the potential protective effect of Fuzhuan brick tea (FBT) against colitis induced by dextran sulphate sodium (DSS) in mice. ICR mice were administered FBT orally for 7days before drinking 3% DSS (w/v). The FBT significantly attenuated the symptoms of colitis including diarrhoea, rectal bleeding and loss of body weight. FBT reduced the shortening of colon length and alleviated the histopathological damages. The myeloperoxidase activity, nitric oxide and malondialdehyde level in colon tissues were also significantly decreased by FBT. Besides, FBT treatment obviously suppressed the expression of the inflammatory cytokines such as TNF-, IL-1 and IFN-. Our results provide a safe and efficient method for preventing and treating colitis.

关键词： Mesenchymal stem cells   Dextran sulfate sodium (DSS)-induced colitis   Toll-like receptors   Poly(I:C)   Indoleamine 2,3-dioxygenase   Intraperitoneal route  

摘要： Mesenchymal stem cells (MSCs) have been used experimentally for treating inflammatory disorders, partly owing to their immunosuppressive properties. The goal of the study was to determine whether TLR ligands can enhance the therapeutic efficacy of bone marrow-derived MSCs for the treatment of inflammatory bowel disease. Mice (C57BL6) were administered with 4% dextran sulfate sodium (DSS) in drinking water for 7 days and injected with MSCs on days 1 and 3 following DSS ingestion. Our results demonstrated that among various TLR ligands, MSCs treated with polyinosinic-polycytidylic acid [poly (I:C)], which is a TLR3 ligand, more profoundly induced IDO, which is a therapeutically relevant immunosuppressive factor, without any observable phenotype change in vitro. The poly (I:C)-treated MSCs attenuated the pathologic severity of DSS-induced murine colitis when injected i.p. but not i.v. In summary, preconditioning MSCs with poly (I:C) might improve their efficacy in treating DSS-induced colitis, and this effect at least partly depends on the enhancement of their immunosuppressive activity through increasing their production of IDO.

关键词： Power Spectral Density   MQCL   Dry turning   Clean manufacturing   Surface metrology  

摘要： The paper analyses the influence of clean manufacturing (green manufacturing) methods on the surface morphology of duplex stainless steel. The surface quality was compared using Power Spectral Density for dry and MQCL turning process. Analysis of signal power on the surface demonstrated that the wavelength is higher for dry turning than for machining using MQCL method. The amplitude of the feed ingredient is visible in the higher range of the feed, at low feed rates dominate tool vibration with the wear of the cutting tool point. In the paper the authors proved that using PSD it is possible to characterize turning regarding applied cooling methods, by qualitative and quantitative comparison of this function for inspected surfaces. Additionally amplitudes of analyzed surfaces are approximately from 1.81 gm to 2.10 mu m for different feed values. (C) 2016 Elsevier Ltd. All rights reserved.