关键词： Pattern recognition   pattern classification   principle of homology continuity   neural networks  

摘要： Homology Continuity is a fundamental property of the nature, but few of the traditional pattern recognition algorithms were aware of it. Firstly, this paper gives a brief description to the Principle of Homology Continuity (PHC), and tries to mathematically redefine it. Then, we introduce a PHC-based pattern learning method - Geometrical Covering Learning (GCL), following the Hyper sausage neural network as an instance of GCL. Lastly, we propose a GCL solution to the "two-spirals" pattern recognition problem. The final experimental results show that the new method is feasible and efficient.

关键词： Deformation  

摘要： The scope of the present work is to apply tested techniques of pattern recognition on bathymetric data from the Eratosthenes Seamount to (a) detect topographic highs and linear-curvilinear lineaments present on the seabed, (b) evaluate the morphostucture of the seamount and its relation with the degree of deformation the region has suffered, and (c) to check if shallow salt movements are associated with specific patterns on bathymetric data. Our scope is implemented by applying a two-step procedure on bathymetric data. Initially, the topographic highs in the study area are detected and their geomorphologic attributes (orientation, average slope, eccentricity, and shape complexity) associated with the degree of seabed deformation are computed. Then, quantitative attributes (slope, aspect, and their derivatives) are combined to automatically detect seabed morphologic structures (lineaments, highs, or depressions), which are potentially related to the presence of geological faults or triggered by other subsurface processes. Based on the analysis in this work, two major segments (the northern and the southern) are identified on the Eratosthenes Seamount and related to E-W trending oblique faults. These two segments are highly deformed according to the quantitative estimation of the geomorphologic attributes. Furthermore, ENE-WSW to NE-SW and WNW-ESE to NW-SE lineaments are identified and limit this prominent topographic high. Smaller topographic highs accompanied by topographic depressions, north and southwest of the Eratosthenes Seamount are also detected, showing medium to strong deformation and reflecting a similar geodynamic activity in this area. As a corollary, a comparison of the bathymetric patterns shows that the present seabed morphology north of the Eratosthenes Seamount relates to shallow salt movements, which create a chaotic pattern. This pattern is expressed by short and curved normal faults, shear zones, possible small-scale reverse faults, massive extru

关键词： hyperspectral airborne imaging   pattern recognition of forest stand objects   parameterization of forest environments  

摘要： Model applications of airborne hyperspectral remote sensing data for the recognition of forest stand objects and parameterization of the environmental role of forests in climatic models are discussed. The article is focused primarily on a comparison of the data obtained by ground-based forest inspections and the results of processing of hyper-spectral images of a test area. The examples of such a comparison intended to determine the net primary productivity of forests and other parameters characterizing the biodiversity of forest vegetation are considered.

关键词： ANTICOAGULANTS (Medicine)   PHOSPHOLIPID antibodies   CHROMATOGRAPHIC analysis   PHOSPHATIDYLSERINES   PROTHROMBIN  

摘要： Background: Whether antibodies directed to beta 2-Glycoprotein I (a beta 2GPI) are responsible for LA activity is not well defined. However, in the absence of such antibodies the molecule responsible for LA phenomenon is unknown. Objective: The aim of this study was the biochemical identification of the target antigen epitope of aPL responsible of LA activity in the absence of a beta 2GPI antibodies together with the biological and clinical characteristics of these patients in comparison with classical triple positive patients. Patients/methods: A comparison of patients with LA without (LA+/a beta 2GPI-) and those with (LA+/a beta 2GPI+) associated a beta 2GPI antibodies was performed. Size exclusion chromatography and analytical chromatography were used to identify the molecule with LA activity in patients LA+/a beta 2GPI-. Results and conclusions: Analytical size-exclusion chromatography revealed a peak of 996Kd with LA activity perfectly overlapping that of IgM anti phosphatidylserine/prothrombin (aPS/PT) antibodies. Similarly, all the 25 LA+/a beta 2GPI-patients were positive for aPS/PT antibodies. LA+/a beta 2GPI-compared to 33 LA+/a beta 2GPI+ patients turned out to be significantly older, with a lower rate of previous thromboembolic events and a weaker LA activity. Search for aPS/PT and a beta 2GPI antibodies in patients with LA is useful to identify two subgroups of LA at different risk of thromboembolic events.

关键词： Cation-dependent mannose-6-phosphate receptor   Bacterium   Antimicrobial peptide   Polysaccharides  

摘要： The cation-dependent mannose-6-phosphate receptor (CD-MPR) is a member of the P-type lectin family. As a type I transmembrane glycoprotein, it functions in the delivery of newly synthesized acid hydrolases from the trans-Golgi network to endosomes for their subsequent transfer to the lysosome by binding the mannose-6-phosphate receptor-recognition moieties in the hydrolases. However, the functions of CD-MPR in immune responses are seldom reported. In the present study, we identified a CD-MPR-like molecule in Marsupenaeus japonicus and designed it as MjCD-MPR. It was significantly upregulated after challenge with Vibrio anguillarum at the mRNA and protein levels. Knockdown of MjCD-MPR resulted in a significant increase in the amount of V. anguillarum in the hemolymph of shrimp, which suggested that MjCD-MPR plays a role in shrimp antibacterial defense. The recombinant extracytoplasmic region of MjCD-MPR could bind gram-positive and gram-negative bacteria by interaction with peptidoglycan, lipopolysaccharide, and lipoteichoic acid. MjCD-MPR showed no direct bacteriostatic or bacteriocidal activity. Knockdown of MjCD-MPR decreased the expression levels of several antimicrobial peptides (Alf-C1, Alf-E1, Crustin I-2, and Crustin I-3), suggesting that MjCD-MPR promotes the expression of antimicrobial peptides in shrimp. In summary, working as a pattern recognition receptor, MjCD-MPR recognizes invading bacteria and triggers the expression of AMPs against bacterial infection in shrimp.

关键词： feature descriptor   nonuniform illumination   phase congruency   monogenic signal   histogram of oriented gradients  

摘要： A new descriptor for describing features in gray-scale images that is invariant to nonuniform illumination is proposed. The suggested method for the feature descriptor design is based on a local energy model which is a biologically plausible model of the visual system. The algorithm for feature detection and construction of the descriptor uses the scale-space monogenic signal framework and a modified algorithm for calculation of the histogram of oriented gradients based on the phase congruence of the signals. The results of computer simulation show that the proposed descriptor provides excellent detection and matching of features at nonuniform illumination, noise, and minor geometric distortions in comparison with known descriptors.

关键词： chemokines   dendritic cells   dsRNA   ovarian cancer   PRR  

摘要： Inflammation and cancer are inter-related, and both pro- and anti-tumorigenic effects are possible in different contexts, highlighting the importance of characterizing specific inflammatory pathways in distinct tumor types. Malignant cells and non-cancerous cells such as fibroblasts, infiltrating leukocytes (i.e., dendritic cells [DC], macrophages, or lymphocytes) and endothelial cells, in combination with the extracellular matrix, constitute the tumor microenvironment (TME). In the last decades, the role of the TME in cancer progression has gained increased attention and efforts directed at abrogating its deleterious effects on anti-cancer therapies have been ongoing. In this context, we investigated the potential of mouse and human ovarian cancer cells to produce inflammatory factors in response to pathogen recognition receptor (PRR) signaling, which might help to shape the biology of the TME. We determined that mouse ovarian tumors generate chemokines that are able to interact with receptors harbored by tumor-associated DCs. We also found that dsRNA triggers significant pro-inflammatory cytokine up-regulation in both human and mouse ovarian tumor cell lines, and that several PRR can simultaneously contribute to the stimulated inflammatory response displayed by these cells. Thus, dsRNA-activated PRRs may not only constitute potentially relevant drug targets for therapies aiming to prevent inflammation associated with leukocyte recruitment, or as co-adjuvants of therapeutic treatments, but also might have a role in development of nascent tumors, for example via activation of cancer cells by microbial molecules associated to pathogens, or with those appearing in circulation due to dysbiosis. © 2018 Impact Journals LLC. All rights reserved.

关键词： Aminoglycoside antibiotics   DNA-conjugated gold nanoparticles   Colorimetric sensor array   Pattern recognition methods  

摘要： Aminoglycoside antibiotics (AAs) abused in animal husbandry can cause antibiotic residues in animal derived foods, which do harm to human beings' health. Therefore the detection of AAs residues in the animal-origin foods, such as milk, eggs and meat is necessary. We used two single-stranded DNA (ssDNA) oligonucleotides as nonspecific receptors to develop a simple colorimetric sensor array based on gold nanoparticles (AuNPs) for identification and quantification the AAs. Different AA addition triggered the DNA detaching from AuNPs then resulted in different degree salt induced aggregation of AuNPs. The aggregation induced spectral changes of AuNPs with five AA addition were analyzed based on pattern recognition techniques, fisher linear discriminant analysis (FLD) and hierarchical cluster analysis (HCA). The results indicated that colorimetric sensor array has successfully identified five AAs at a concentration range of 120-280 nM. Five AAs in aqueous solution and complex milk matrix can be identified with an accuracy of 100%. More importantly, our developed sensor array is sufficiently sensitive for the discrimination of pure streptomycin (STR), binary mixtures of STR and gentamicin (GEN) at a total concentration of 120 nM. (C) 2018 Elsevier B.V. All rights reserved.

关键词： Graph classification   Structured pattern recognition   Graph neural network   Random network   Relational learning  

摘要： Taking inspiration from the probabilistic principles underlying the topological regularities observed in random networks, the paper presents a simple and efficient Bayesian framework for the classification of (small) labeled random networks. The proposed "graphical model" relies on a Parzen window estimate of the pairwise vertex-vertex probability distribution under an implicit Markov assumption. Experiments show that, in spite of its simplicity, the approach is at least as accurate as the state-of-the-art machines. The highest average recognition accuracies to date were obtained on the friendly + unfriendly Mutagenesis classification task. (C) 2018 Elsevier B.V. All rights reserved.

关键词： GIS   大数据   模式识别   深度卷积网络   局部放电  

摘要： 随着局部放电检测技术和大数据技术的推广,变电站现场气体绝缘组合电器（GIS）的局部放电检测数据不仅数量庞大,而且数据来源复杂,因此传统的局部放电模式识别方法已难以满足需求。鉴于此,提出了一种基于深度卷积网络的局部放电大数据模式识别方法,构建了应用于局部放电模式识别的深层卷积网络模型,同时应用深度自编码器对模型参数进行初始化,利用多层卷积神经网络提取局部放电大数据的深层特征以提高复杂数据源下的识别正确率。通过真型GIS模型实验、变电站现场带电检测和典型干扰实验获取了大量局部放电检测数据,组成复杂数据源的测试样本,并对所提方法进行了实验分析。实验结果表明：与传统的模式识别方法相比,新所提的方法在处理复杂数据源样本任务中识别正确率更高,且识别正确率提高值随样本数据的增加而增大,更适合于大数据平台的工程应用需求。