关键词： Syntax score   Acute coronary syndrome   T -wave amplitude   T/R ratio  

摘要： Objectives and background: Our objective was to determine the diagnostic significance of a low T-wave amplitude (TWA) and T/R ratio, defined as the amplitude ratio between the T waves and the R waves, in patients with acute non-ST elevation myocardial infarction (ANSTEMI). Syntax score (SS) shows the extension of coronary artery disease. Previously, low TWA and T/R ratios were demonstrated to be inversely proportional to the risk of sudden cardiac arrest in different cardiac disease conditions. Methods: 266 patients were retrospectively included with ANSTEMI between July 2021 and December 2022. SS-1 and SS-2 scores were calculated using the angiographic and clinical data of the patients. The patients were stratified into tertiles based on their median SS-1 scores as lower, moderate, and higher SS-1 tertiles. ECG parameters, including TWAs and T/R ratios in leads II and V5, were measured digitally. TWA and T/R ratios were compared with SSs among the tertiles. Results: TWA and T/R ratios in leads II and V5 were significantly lower across the increasing SS-1 tertiles (p < 0.001 for TWA in lead II) (p < 0.001 for T/R ratio in lead II) (p = 0.014 for TWA in lead V5) (p = 0.002 for T/R ratio in lead V5).ROC analysis identified T/R ratios in leads II and V5 of 0.254 (AUC: 0.758, p <0.001) and 0.201 (AUC: 0.635, p < 0.015), respectively. Conclusion: A low T/R ratio, particularly in lead II due to its greater AUC, better predicts moderate-to-high SS-1 in patients with ANSTEMI.

关键词： 21st century skills   Educational robotics coding   Elementary school students   Sociocultural   Cognitive   Affective  

摘要： This study aims to examine the effects of educational robotics activities on students' 21st century skills. In the study, explanatory mixed method design was used. As a quantitative data collection tool, the 21st century skills scale was utilized [47]. In addition to quantitative data, qualitative data were collected from the teachers and students through semi-structured interviews. Within the scope of the research, students participated in robotic design courses with Arduino over the learning management system for ten weeks and participated in a competition with their products at the end of the activity. The activity was held with the participation of 62 students and 10 teachers. The findings of the study showed that educational robotic activities caused a significant increase in the affective domain of the students. While it did not cause any significant increase in the cognitive and sociocultural domains, the average scores of students increased on post-tests compared to the pretests for these two domains. In addition, students' 21st century skills did not differ according to gender. Although there is no statistically significant difference in pretest-posttest results due to grade level, an increase was observed in posttest averages at each grade level. The observed increase in the post-tests, although not statistical, reveals the positive effect of educational robotic coding in terms of students' 21st century skills. To support the results of the quantitative data, the analysis of the qualitative data revealed a consensus of both teachers and students on the contribution of such applications to the advancement of contemporary skills. In conclusion, the results of this study show that educational robotic coding can be used to develop 21st century skills of elementary school students.

关键词： Social network analytics   SNS co-occurrence similarity   Tourism demand forecasting   Space-time forecasting  

摘要： In the digital era, social network service (SNS) significantly influences travel behavior. Understanding SNS spillover effects is crucial for accurate tourism demand prediction. This study introduces SNS co-occurrence similarity (SNS-COS) to capture the spillover effects and demonstrates a comprehensive tourism demand forecasting framework that combines econometric and AI models to handle spatial and temporal data. By classifying attractions into different ranks, it effectively captures varying spillover effects. Empirical verification shows significant improvements in forecasting accuracy, especially for low-ranked attractions, providing valuable insights for enhancing tourism demand forecasting and informed decision-making in the tourism industry.

关键词： estimated glomerular filtration rate   kidney function   radiation therapy   Wilms tumor  

摘要： BackgroundAdult survivors of unilateral, nonmetastatic, non-syndromic Wilms tumor (WT) treated with whole abdomen radiation therapy (WART) are at risk for impaired kidney function. The impact of bias and accuracy on estimated glomerular filtration rate (eGFR) among adult survivors of WT has not been well *** clinically evaluated male and female WT survivors with creatinine and cystatin C, calculated eGFR using the Chronic Kidney Disease-Epidemiology equations with and without cystatin C, and measured 99mTc diethylenetriamine pentaacetic acid (DTPA) plasma clearance. WT survivors treated with unilateral nephrectomy (UN), non-nephrotoxic chemotherapy (NNC) and WART or treated with UN, no radiation therapy, and NNC were enrolled. Correlations between 99mTc DTPA clearance and eGFR were calculated. Bias and the percentage of eGFR calculations that differed from the 99mTc DTPA clearance by 10% or less (P10) or 30% or less (P30) (accuracy) were *** female WT survivors, none of the eGFR calculations was statistically significantly correlated with 99mTc DTPA clearance. Among both unirradiated and WART-treated male WT survivors, 99mTc DTPA clearance correlated well with eGFR calculations that included creatinine. eGFR calculations that included creatinine were positively biased among female participants compared to 99mTc DTPA clearance, and no P30 was greater than 90% among either irradiated males or *** female survivors of unilateral, nonmetastatic, non-syndromic WT who have undergone UN, eGFR is poorly correlated with, is positively biased, and lacks sufficient accuracy, compared to 99mTc DTPA clearance.

关键词： enlightened leadership   effective chairs   board leadership   mantras  

摘要： Despite an increasing remit and recognition of the role of the board Chair, resources that effective Chairs of the 21st century deploy remain inadequately explored in the existing literature. This article addresses this gap through the innovative use of 57 face-to-face, elite interviews with board members and provides new insights into the best practices of Chairs of the largest listed companies in the United Kingdom. The findings of the study indicate that effective leadership of boards requires an enlightened approach, with seven Mantras of effective board leading being commonly employed. These Mantras are-support for the CEO, lead with values, exercise influence (not power), compose diverse boards, communicate inclusively, resolve conflicts intuitively and reflect and course correct. The article makes a three-fold contribution: to resource-based theory and enlightened leadership theory, to the literature on board Chair effectiveness and praxis of leading in the 21st century.

摘要： Natural history provides an important basis for observing interactions between organisms in their environments. Biotropica recently inaugurated a new paper category called "Natural History Field Notes" to provide an outlet for such studies. Depicted here are drawings and observations by the author from research ***

关键词： Neoadjuvant Immunochemotherapy   Efficacy Prediction   Graph Convolutional Networks   Early Prediction  

摘要： Accurate preoperative prediction of pathological complete response (pCR) following neoadjuvant immunochemotherapy is crucial for refining and customising perioperative treatment decisions. However, the challenge persists in developing reliable, interpretable, and intelligent imaging markers using early-stage computed tomography (CT). Considering the dynamic evolution of tumours during treatment can offer additional discriminative insights, modelling the spatial and temporal relationships in pre- and post-neoadjuvant treatment CT images may help address these challenges. This study proposes an adaptive spatio-temporal aware graph inference framework (A(2)ST-GCM) to learn potential correlations between tumour regions in the same period and across periods, generating an adaptive spatio-temporal topology, and effectively aggregating features. Specifically, the model first utilises the adaptive spatial graph convolution module (AS-GConv) to capture irregular spatial dependencies within tumour regions before and after treatment. Subsequently, the adaptive spatio-temporal graph convolution module (AST-GConv) is employed to model dynamic dependencies over time, effectively exploring the complementarity and correlation mechanisms among multiple spatio-temporal features, ultimately obtaining a spatio-temporal graph representation containing tumour heterogeneity information. Furthermore, this paper introduces a novel weighted loss function, effectively alleviating the class imbalance issue in predicting pCR. Quantitative experimental results demonstrate the outstanding performance of our model in pCR prediction. To the best of our knowledge, this paper represents the first attempt to apply graph networks to predicting pathological response in neoadjuvant immunochemotherapy. It provides a potential auxiliary tool to evaluate pathological response, aiming to identify individuals who could benefit from surgery avoidance, thereby offering significant clinical benefits for patients

关键词： 精细化管理   全面预算   预算管理  

摘要： 全面预算管理是国有企业实现资源优化配置、提高经营效率和增强市场竞争力的重要工具。在当前的经济环境下，全面精细化预算管理想要维持企业长期而稳定的发展，就免不了需要企业加强自身内部的管理、完善管理体系、制定好可持续发展的战略目标。对此，本文就精细化预算管理在企业财务管理中的应用展开分析，探讨其存在的问题并提出改进措施，以期为企业全面预算管理尽绵薄之力。

关键词： 国有企业   全面预算管理   管理会计   高质量发展  

摘要： 高质量发展时代背景下，国有企业作为社会经济重要支柱力量，应当加强包括预算管理在内的财务管理工作，以此为基础推进业财融合管理，夯实核心竞争力，培育发展动能。基于这一背景，文章主要分析我国国有企业在全面预算管理方面存在的不足，并有针对性地提出对策建议。

关键词： 大数据   财务共享模式   企业财务信息化   数据平台   业财一体化建设  

摘要： 抓住技术进步带来的机遇是企业与时俱进的关键。大数据的广泛应用加速了企业财务管理模式的转型升级，财务共享中心建设逐渐成为各企业争相探索的焦点。基于此，本文首先概述了大数据背景下企业财务信息化的发展现状以及大数据的影响。其次，介绍了财务共享模式下企业财务信息化的基础构建，明确了数据共享与整合的技术框架以及财务信息系统的优化和集成，并分析了基于财务共享模式的企业财务信息化建设的难点，包括缺乏专业人才、资金匮乏、业务规模有限以及增加企业财务风险。最后，提出了基于财务共享模式的企业财务信息化建设策略，建议企业要建立安全可靠的数据平台，优化数据质量管理体系，实现财务数据的共享与集成，优化财务业务流程，开展业财一体化建设。本文研究旨在帮助企业应对大数据时代的挑战，有效实施财务共享模式下的企业财务信息化建设。