关键词： Non-ST segment elevation myocardial infarction   culprit artery   occlusion  

摘要： AIM: To study the effect of timing of percutaneous coronary intervention (PCI) to prognosis of Non-ST segment elevation myocardial infarction (NSTEMI) patients. METHODS: 295 Patients were derived from our hospital who were diagnosed as NSTEMI and accepted PCI therapy in 24 hours from admission during March 2017 to May 2020. According to results of coronary angiography, patients with NSTEMI were divided into culprit artery occlusion (CO, n = 117) and non-culprit artery occlusion (N-CO, n = 178) two groups and then according to timing of PCI into three categories: <6 h, 6-12 h and 12-24 h from admission. We defined major adverse cardiovascular events (MACE) in 1 year follow. RESULTS: In this study, with earlier time to PCI, the incidence of MACE was lower in NSTEMI patients with CO. The incidence of MACE was higher in the CO group than in the N-CO group (25.8% vs. 36.8%, p = 0.046). The incidence of MACE was 11.8% in T1 (<6 h) group (n = 50), less than 29.4% in T2 (6-12 h) group (n = 30) and 43.4% in T3 (12-24 h) group (n = 215), with a statistically significant difference (p = 0.044). However, this phenomenon does not occur in N-CO group. As the duration of PCI increased, patient survival decreased progressively over the course of follow-up in NSTEMI with CO (p = 0.048). CONCLUSIONS: Our study found that early PCI improves the prognosis of NSTEMI patients with culprit artery occlusion.

关键词： Myocardial infarction   STEMI   Sex differences   Diagnosis   Treatment   Prognosis  

摘要： Introduction and objectives: Sex differences among patients with acute myocardial infarctions remain a matter of debate. Inequalities in presentation, diagnosis, treatment, and prognosis are frequently observed, contributing to a worse prognosis in women. The aim of this study was to investigate sex-related differences in Portuguese ST-segment elevation myocardial infarction (STEMI) patients. Methods: The authors conducted a retrospective analysis of STEMI patients included in the Portuguese Registry on Acute Coronary Syndromes, between October 2010 and 2022. The two co-primary endpoints were in-hospital and one-year mortality. Results: A total of 14 470 STEMI patients were studied. Women were underrepresented with 3721 individuals (25.7%). They were significantly older (70 vs. 62 years, p<0.001), with higher prevalence of cardiovascular risk factors, and underwent less frequently coronary angiography (84.4% vs. 88.5%, p<0.001) and guideline-directed medical therapy (e.g., aspirin 92.5% vs. 95.4%, beta blockers 79.2% vs. 83%, p<0.001). Furthermore, they experienced more complications, such as congestive heart failure (23.4% vs. 14.6%), ischemic stroke (47% vs. 40%), and in- hospital mortality (8.5% vs. 4.1%) (p<0.001 for all comparisons). Similarly, they presented higher one-year mortality (11.5% vs. 6.3%, p<0.001). However, after a multivariate analysis testing significant clinical variables, female sex remained an independent predictor for in-hospital (odds ratio=1.633;95% CI [1.065-2.504];p=0.025), but not for one-year mortality. Conclusions This analysis reveals sex-related disparities in Portuguese STEMI patients. Despite limitations inherent to registry-based analysis, women were significantly older, with increased cardiovascular risk, less treated, and with higher in-hospital mortality. These disparities should be a concern for clinicians to further improve outcomes and move toward equitable medical care.

关键词： St37 steel   Quince extract   Green inhibitor   EIS   Temperature   Corrosion kinetics   Quantum chemical calculation   Molecular dynamic simulation  

摘要： This study explored the corrosion behavior of low-carbon steel in a 1 M hydrochloric acid (HCl) solution with increasing temperatures, using varying concentrations of Quince Extract (QE) as an eco-friendly, natural corrosion inhibitor. The extract, scientifically known as Cydonia oblonga, contains functional groups such as amino acids and flavonoids, which contribute to its corrosion-inhibiting properties. These functional groups were analyzed using Fourier Transform Infrared Spectroscopy (FTIR). Electrochemical impedance spectroscopy (EIS) and polarization tests were conducted to assess the inhibition efficiency of QE within a temperature range of 308-328 K. The electrochemical results revealed that the inhibition efficiency of QE decreases with rising temperatures but improves with higher extract concentrations in the solution. According to polarization test data, at a QE concentration of 1000 ppm, the inhibition efficiency reached 91 % at 308 K but dropped to 81 % when the temperature increased to 328 K. The adsorption of QE onto the low-carbon steel surface was modeled using the Langmuir isotherm. Activation and thermodynamic parameters were calculated to analyze the interaction between the inhibitor and the metal surface. The Delta G degrees ads values at different temperatures were approximately -21 kJ & sdot;mol- 1, indicating physical adsorption. The activation energy (Ea) was found to increase from 37.40 kJ & sdot;mol- 1 in the absence of QE to 72.36 kJ & sdot;mol- 1 at a QE concentration of 1000 ppm, further supporting the physical adsorption mechanism. To evaluate the effect of temperature on the adsorption of the inhibitor onto the steel surface, molecular dynamics (MD) simulations were performed. The results identified 4-O-caffeoylquinic acid (CQA) as the most effective component among the QE derivatives for corrosion inhibition. Additionally, Monte Carlo (MC) and MD simulations confirmed a decrease in inhibition efficiency with increasing temperature,

关键词： developmental state   embedded autonomy   hegemony   inclusive development   inclusiveness   institutional regime   strategic-relational approach   sustainable development  

摘要： Motivation: This article contributes to the ongoing debate on the institutional preconditions for inclusive and sustainable development in the global periphery, countries that are in a subordinate position within global capitalism. Purpose: The authors argue that deliberations pertaining to the effectiveness, inclusiveness, and sustainability of economic development must take into account the political-economic contexts of specific peripheral countries. The article goes on to further conceptualize inclusive late industrialization processes and operationalize institutional setups for industrial policy to make it more useful from a policy perspective. Approach and methods: Our conceptual framework draws on neo-Gramscian and materialist state theory, the developmental regime approach, and other contributions on the necessary conditions for effective industrial policy of late industrializers, particularly in sub-Saharan Africa. Findings: We contend that the peripheral states' strategic selectivity often severely limits the emergence of comprehensive industrialization regimes that have extensive elements of embedded autonomy and hegemony. In fact, pro-developmental social forces are likely to be more successful in promoting selective industrialization projects in peripheral contexts. Notwithstanding the comprehensiveness of industrialization regimes, we propose the operationalization of industrial policy institutions with regard to their degree of inclusiveness, decentralization, managerialism, and state-led production. We conceptualize the different ways actors may be included or excluded at different scales of industrial policy institutions. In doing so, potential trade-offs within and between these institutional areas are highlighted, enhancing the policy relevance of the debate. Policy implications: From a strategic policy perspective, the exclusive nature of bureaucratic-authoritarian industrialization regimes of the 20th century needs to be avoided in latecomer ind

关键词： Out-of-hospital cardiac arrest   Prognostic score   STEMI  

摘要： Background Patients resuscitated after out-of-hospital cardiac arrest (OHCA) have a poor prognosis, with high death rates. Multiple scoring systems have been developed to predict survival in all-comers with OHCA. Acute coronary syndromes and ST-segment elevation myocardial infarction (STEMI) are the primary causes of OHCA. Recently, a specific prognostic score (Tran risk model) was developed for patients with STEMI-related OHCA. Aim To compare the accuracy of established non-STEMI-specific prognostic scores (OHCA, modified CAHP and NULL-PLEASE) with the Tran risk model in predicting in-hospital death among patients with STEMI-related OHCA. Methods This was an observational single-centre study including 315 consecutive patients treated for STEMI-related OHCA. The OHCA score was calculated for 310 patients (98.4%), the NULL-PLEASE and modified CAHP (mCAHP) scores were calculated for 308 patients (97.8%) and the Tran risk model score was calculated for 306 patients (97.1%). A C-statistic analysis was performed to determine score performance. Results The area under the curve (AUC) for the Tran risk model was 0.75 (95% confidence interval [CI] 0.69-0.79). The AUCs for the OHCA, mCAHP and NULL-PLEASE scores were 0.74 (95% CI 0.69-0.80), 0.74 (95% CI 0.69-0.80) and 0.76 (95% CI 0.71-0.82), respectively. There was no significant difference in AUCs between the Tran risk model and the mCAHP score (P = 0.95), the NULL-PLEASE score (P = 0.42) or the OHCA score (P = 0.93). Similarly, no significant difference was observed between the mCAHP, NULL-PLEASE and OHCA scores. Predictors of death were no-flow duration, diabetes, blood lactate, femoral access and age > 75 years. Conclusions The OHCA, NULL-PLEASE and mCAHP scores and the Tran risk model showed moderate to good performance in predicting in-hospital death in patients with STEMI-related OHCA. No differences in accuracy were found between non-STEMI-specific scores and the Tran risk model developed for patients with STEMI-rela

关键词： Caribbean   Slavery   Suitability analysis   Circuit analysis   LiDAR   GIS   Colonialism  

摘要： On the Caribbean island of St. Croix, archival documents reference settlements of runaway enslaved Africans in the mountainous range known as Maroon Ridge. These settlements provide an important record of Afro-Atlantic resistance to enslavement. However, as both intentionally secluded and ephemeral places of refuge, these maroon settlements are difficult to locate in the archaeological record. Geospatial modeling provides one avenue for understanding African geographies of resistance. Building on prior geospatial modeling efforts, this paper uses a GIS-based multicriteria suitability analysis to characterize the shifting affordances of marronage on Danish colonial St. Croix across the second half of the eighteenth century. By considering how the island landscape "looked" to those seeking refuge, we trace how possibilities for refuge were distributed through space and over time. In this paper, we develop affordance heuristics to model refuge using digitized historic maps and publicly available LiDAR data. The resulting model suggests shifting maroon refugia sites over time and demonstrates how geospatial approaches, paired with historical archives, can model historic affordances across time.

关键词： Capparis spinosa L.   Extraction optimization   Antioxidant   Anticorrosion   Doehlert design   SEM-EDX  

摘要： Eco-friendly inhibitors have gained great research interest during the past decades. Natural-based corrosion inhibitors are produced from renewable sources and concurrently offer high performance and low environmental impact. In this work, ethanol extract of Capparis spinosa L. leaf was employed to impede St37 steel corrosion in 1 M H2SO4 for the first time. The corrosion inhibition capacity of Capparis spinosa L. has been tested through multiscale assay techniques, i.e. gravimetric measurements, electrochemical analysis, scanning electron microscopy (SEM) and energy dispersive x-ray spectroscopy (EDX), potentiodynamic polarization tests and Fourier transform infrared (FTIR). The liquid-solid ratio, extraction temperature and extraction time were optimized to extract antioxidant phenolic compounds from Capparis spinosa L. leaf using a Doehlert experimental design to attain the optimum concentration of each extract. High Performance Liquid Chromatography-Diode Array Detection (HPLC-DAD) was employed to identify the major components of Capparis spinosa L. extract (CSE) at optimal extraction conditions. Secondly, CSE was evaluated on the corrosion rate at different concentrations, temperatures, and times. Experimental results revealed that the CSE can be considered as good green inhibitor. Depending on electrochemical experiments, when CSE is present, corrosion current densities are highly reduced. CSE acts as a mixed-type inhibitor, effectively reducing the corrosion of St37 steel surfaces in 1 M H2SO4. At a concentration of 500 ppm CSE and 60 degrees C, a high inhibition efficiency of 95.63 % was achieved. Surface analysis was carried out by FT-IR and SEM-EDX confirming that the St37 steel protects from corrosion.

摘要： 107702

关键词： Action recognition   Two-stream network   Multi-scale   Spatial-temporal information  

摘要： Human action recognition (HAR) is an important task in the field of computer vision, and its primary goal is to analyze and understand human activities in videos. In addition to containing the spatial information of static images, videos also contain unique temporal information, which makes the information contained in the videos even richer. However, the training cost required to fully learn the spatial-temporal information of the videos is quite expensive for a model. In light of this, we propose a novel two-stream network structure to effectively capture the spatial-temporal information in video data. We perform masked autoencoders (MAE) pre-training, aiming to reduce the training burden of the model through this asymmetric encoder-decoder pre-training method. In addition, we propose a new multi-scale decoder component that combines transposed convolutional upsampling and convolutional downsampling. It fully utilizes the multi-scale features of the encoder to achieve excellent performance. On two challenging video datasets, Kinetics 400 (K400) and Something-Something-v2 (SSv2), we achieve state-of-the-art performance with 85.9\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\%$$\end{document} and 75.3\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\%$$\end{document} Top-1 accuracy, respectively.