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关键词： LSID   Metadata   RDF   Resolution   Export schema   View   Trigger   Biology   Systematics  

摘要： Life science identifier (LSID) is a global unique identifier standard intended to help rationalize the unique archival requirements of biological data. We describe LSID implementation architecture such that data managed by a relational database management system may be integrated with the LSID protocol as an add-on layer. The approach requires a database administrator (DBA) to specify an export schema detailing the content and structure of the archived data, and a mapping of the existing database to that schema. This specification can be expressed using SQL view syntax. in effect, we define a SQL-like language for implementing LSIDs. We describe the mapping of the view definition to an implementation as a set of databases triggers and a fixed runtime library. Thus a compiler for a domain-specific language could be written that would reduce the implementation of LSIDs to the task of writing SQL view-like definitions. (C) 2008 Elsevier Inc. All rights reserved.

关键词： expectation conditional maximization   genotype   haplotype   HIV-1   lipids   missing identifiers   mixed-effects models   phenotype   population-based genetic association studies  

摘要： This manuscript describes a novel, linear mixed-effects model-fitting technique for the setting in which correlated data indicators are not completely observed. Mixed modeling is a useful analytical tool for characterizing genotype-phenotype associations among multiple potentially informative genetic loci. This approach involves grouping individuals into genetic clusters, where individuals in the same cluster have similar or identical multilocus genotypes. In haplotype-based investigations of unrelated individuals, corresponding cluster assignments are unobservable since the alignment of alleles within chromosomal copies is not generally observed. We derive an expectation conditional maximization approach to estimation in the mixed modeling setting, where cluster assignments are ambiguous. The approach has broad relevance to the analysis of data with missing correlated data identifiers. An example is provided based on data arising from a cohort of human immunodeficiency virus type-1-infected individuals at risk for antiretroviral therapy-associated dyslipidemia.

关键词： 视图安全   信息泄露   k-匿名   准标识符  

摘要： k-匿名是保证视图安全的一种主要手段,如何找出正确的准标识符对k-匿名方法的有效性具有重要意义.针对这一问题,分析了不存在函数依赖和存在函数依赖两种情况下准标识符的组成特征,即当不存在函数依赖时,准标识符由视图间的公共属性组成,当存在函数依赖时,准标识符由视图间的公共属性和秘密信息包含的函数依赖关系的前件属性组成,在此基础上,给出了准标识符的通用求解算法,并用实验证明了算法的有效性和正确性.

标准号: CSA ISO/IEC 15459-5-08-CAN/CSA-2008

关键词： 4  

关键词： Data integration   Entrez LinkOut   Gateway   GUID   Neurodatabases   PubMed  

摘要： This paper describes the NIF LinkOut Broker (NLB) that has been built as part of the Neuroscience Information Framework (NIF) project. The NLB is designed to coordinate the assembly of links to neuroscience information items (e.g., experimental data, knowledge bases, and software tools) that are (1) accessible via the Web, and (2) related to entries in the National Center for Biotechnology Information's (NCBI's) Entrez system. The NLB collects these links from each resource and passes them to the NCBI which incorporates them into its Entrez LinkOut service. In this way, an Entrez user looking at a specific Entrez entry can LinkOut directly to related neuroscience information. The information stored in the NLB can also be utilized in other ways. A second approach, which is operational on a pilot basis, is for the NLB Web server to create dynamically its own Web page of LinkOut links for each NCBI identifier in the NLB database. This approach can allow other resources (in addition to the NCBI Entrez) to LinkOut to related neuroscience information. The paper describes the current NLB system and discusses certain design issues that arose during its implementation.

关键词： biodiversity informatics   DOI   identifiers   knowledge integration   LSID   SemanticWeb   taxonomy  

摘要： A major challenge facing biodiversity informatics is integrating data stored in widely distributed databases. Initial efforts have relied on taxonomic names as the shared identifier linking records in different databases. However, taxonomic names have limitations as identifiers, being neither stable nor globally unique, and the pace of molecular taxonomic and phylogenetic research means that a lot of information in public sequence databases is not linked to formal taxonomic names. This review explores the use of other identifiers, such as specimen codes and GenBank accession numbers, to link otherwise disconnected facts in different databases. The structure of these links can also be exploited using the PageRank algorithm to rank the results of searches on biodiversity databases. The key to rich integration is a commitment to deploy and reuse globally unique, shared identifiers [such as Digital Object Identifiers (DOIs) and Life Science Identifiers (LSIDs)], and the implementation of services that link those identifiers.

关键词： 合成材料   标识符   土力学   识别方法  

标准号: GB/T 14798-2008

摘要： 本标准规定了土工合成材料需标明的信息，用于使用者现场鉴别产品是否与订货相符。本标准的主要目的是为了准确鉴别土工合成材料，例如鉴别没有包装的或者不是成卷的土工合成材料产品。 本标准规定的信息不能代替技术数据，也不能用于验证产品与技术要求的符合程度。

关键词： 理查德·尼布尔   基督   文化   关系类型  

摘要： 基督教与文化的关系问题是一个非常复杂的问题,这不仅仅是由于二者之间的关系"剪不断、理还乱",而且也由于"基督教"与"文化"这对范畴十分难以界定和把握。理查德·尼布尔在《基督与文化》一书中对基督和文化进行了界定,提出了基督和文化之间的五种关系类型,为深入地探讨宗教与文化之间的关系提供了方法上的和思想上的借鉴。

关键词： DOI   网络   惟一与兼容   论文引用率  

摘要： DOI的主要目的是惟一标识网络环境下的各种信息资源实体,包括各种物理和数字资源,它包括四个部分:数字对象标识符的编码规则、解析系统、元数据框架以及分配和管理机制,其显而易见的惟一和兼容性,正在成为研究人员查找文献、提高论文引用率的最便捷的工具。