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关键词： Appendicitis   Eradication Rate   Tigecycline   mITT Population   Clinical Cure Rate  

摘要： Background: Complicated intra-abdominal infections (cIAI) remain challenging to treat because of their polymicrobial etiology including multi-drug resistant bacteria. The efficacy and safety of tigecycline, an expanded broad-spectrum glycylcycline antibiotic, was compared with imipenem/cilastatin (IMI/CIS) in patients with cIAl. Methods: A prospective, double-blind, multinational trial was conducted in which patients with cIAI randomly received intravenous (IV) tigecycline (100 mg initial dose, then 50 mg every 12 hours [q12h]) or IV IMI/CIS (500/500 mg q6h or adjusted for renal dysfunction) for 5 to 14 days. Clinical response at the test-of-cure (TOC) visit (14-35 days after therapy) for microbiologically evaluable (ME) and microbiological modified intent-to-treat (m-mITT) populations were the co-primary efficacy endpoint populations. Results: A total of 825 patients received >= 1 dose of study drug. The primary diagnoses for the ME group were complicated appendicitis (59%), and intestinal (8.8%) and gastric/duodenal perforations (4.6%). For the ME group, clinical cure rates at TOC were 80.6% (199/247) for tigecycline versus 82.4% (210/255) for IMI/CIS (95% CI -8.4, 5.1 for non-inferiority tigecycline versus IMI/CIS). Corresponding clinical cure rates within the m-mITT population were 73.5% (227/309) for tigecycline versus 78.2% (244/312) for IMI/CIS (95% CI -11.0, 2.5). Nausea (31.0% tigecycline, 24.8% IMI/CIS [P = 0.052]), vomiting (25.7% tigecycline, 19.4% IMI/CIS [P = 0.037]), and diarrhea (21.3% tigecycline, 18.9% IMI/CIS [P = 0.435]) were the most frequently reported adverse events. Conclusion: This study demonstrates that tigecycline is as efficacious as imipenem/cilastatin in the treatment of patients with cIAI.

关键词： 社会基础设施   持续性   DOI   IDF   标识符   政策   联盟   技术   分配   商业模式   信息产业  

摘要： IDF已经通过协作行动将一些政策和过程正式化，这些政策和过程是用来帮助RA（Register Agent）联盟的成员确保所有DOI的持续性。DOI的关键一点就是其持续性，这种持续性并非通过技术手段来保证，而是通过一种社会基础设施来给予保证，而这种社会基础设施必须适应这样一种不可避免的事实，即：标识符的分配者在孤立的状态下无法保证其持续性。

关键词： 水文数据库   表结构   标识符   标准   认识  

摘要： 对水利行业技术标准《基础水文数据库表结构及标识符标准》(SL324-2005)编制背景、编制原则与主要特点、主要内容作了介绍,着重举例分析了与全国水文数据库表结构方案3.0版的主要差异, 给出了贯彻标准的几点建议。

关键词： Java obfuscation   program protection   decompilation  

摘要： Decompilation is the process of translating object code to source code and is usually the first step towards the reverse-engineering of an application. Many obfuscation techniques and tools have been developed, with the aim of modifying a program, such that its functionalities are preserved, while its understandability is compromised for a human reader or the decompilation is made unsuccessful. Some approaches rely on malicious identifiers renaming, i.e., on the modification of the program identifiers in order to introduce confusion and possibly prevent the decompilation of the code. In this work we introduce a new technique to overcome the obfuscation of Java programs by identifier renaming. Such a technique relies on the intelligent modification of identifiers in Java bytecode. We present a new software tool which implements our technique and allows the processing of an obfuscated program in order to rename the identifiers as required by our technique. Moreover, we show how to use the existing tools to provide a partial implementation of the technique we propose. Finally, we discuss the feasibility of our approach by showing how to contrast the obfuscation techniques based on malicious identifier renaming recently presented in literature. (c) 2004 Elsevier Inc. All rights reserved.

关键词： INTERNET   COMPUTER programming   FUZZY algorithms   WORLD Wide Web  

摘要： A universal resource identifier (or URI) is a compact string of characters for identifying an abstract or physical resource, providing a simple and extensible means for identifying that resource [1] in the world wide web. In this paper, we present a new modelling approach of extending this identifier to encompass paths of a type of directed labelled fuzzy trees. (c) 2005 Elsevier Ltd. All rights reserved.

关键词： Mean   Identity management systems   Credentialing   Trusted third parties   Credential   personal identity  

摘要： This paper looks at the concepts of entities, identities, identifiers and credentials, their definitions, and how they combine to authenticate an identity to an account, or function, within a service. Credentials can be divided into several different types on the basis of their use, origin and characteristics. In particular, types such as composite, dynamic and derived credentials will be considered, and their applicability within an identity management system. Each credential must be managed through its entire life cycle from initial registration, general use and suspension, to deletion. The notion of public (i.e. freely distributable) and private (i.e. known only to you) aspects of a credential is explored. The bindings, by trusted third parties, of identifiers and public credentials into permits and instruments of proof is explained along with the convenience, but greater exposure, of local information. Several scenarios are analysed in terms of how different types of credentials are employed during the authentication process.

关键词： 数据交换   识别   信息技术  

标准号: ANSI/NISO Z39.84-2005

摘要： Defines the syntax for a character string called the Digital Object Identifier. Policies governing the assignment and use of DOI's are determined by the International DOI Fnd, (IDF) and are outside the scope of this standard.

关键词： polymerase chain reaction (PCR)   short tandem repeats (STRs)   Chinese   allele frequencies   Identifier (TM) PCR amplification kit  

摘要： Allele, frequencies for 15 STR loci, namely D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51,D5S818 and FGA, which are tested for by PE Applied Biosystem's Identifier kit, were obtained from a sample of 325 unrelated Chinese in Hong Kong. (c) 2004 Elsevier Ireland Ltd. All rights reserved.

关键词： 计算机病毒   黑客   加密软件   类标识符   文件夹  

摘要： 最完美的伪装莫过于让别人根本就不知道那是你的文件夹，这样就可以从容的在他们的眼皮地下掩藏我们的秘密，而不让他们发觉。也许你不知道，Windows的“类标识符”就是个很好的伪装大师。

关键词： JaVa   JDK   javac   环境变量   path   classpath   开发环境   Java   Windows   搭建  

摘要： 详细介绍在Java中JDK的安装及环境变量的配置,并给出了具体的操作策略、解决方法及在环境搭建过程中应注意的事项。