课程文献中心 更多>>

关键词： Cognitive function   Depression symptoms   Group-based dual trajectory model   Logistic regression  

摘要： Objective To explore the trends in cognitive function and depression symptoms over time among middle-aged and older adults in China, and to identify populations with differing trajectories of cognitive function and depression symptoms, thereby providing a scientific basis for formulating targeted prevention and control measures. Methods A total of 11 863 individuals aged 45 and above from the China Health and Retirement Longitudinal Study (CHARLS) were included. The Group-based Dual Trajectory Model (GBDTM) was employed to identify the developmental trajectories of cognitive function and depression symptoms, and multinomial logistic regression analysis was utilized to examine the influencing factors of different trajectories. Results The GBDTM identified four trajectory groups: “Poor cognitive function but mild depression symptoms" (Group 1, 32.9%), “Poor cognitive function and severe depression symptoms" (Group 2,10.8%),“Good cognitive function and mild depression symptoms" (Group 3, 40.5%), and “Moderate cognitive function and moderate depression symptoms" (Group 4, 15.7%). Factors associated with a higher likelihood of being classified in the “Poor cognitive function and severe depression symptoms" group included being female (OR =4.70, 95% CI: 3.82-5.78),unmarried (OR =2.09,95% CI: 1.67-2.60), residing in rural areas (OR =4.26, 95% CI: 3.59-5.07), smoking (OR=1.26, 95% CI: 1.02-1.56), having activities of daily living (ADL) disabilities (OR =1.92, 95% CI: 1.39-2.65), and having instrumental activities of daily living (IADL) disabilities (OR =7.43, 95% CI: 5.90-9.35). Conclusion There is a partially “joint development" trajectory relationship between cognitive function and depression symptoms in middle -aged and older adults. Early intervention targeting the influencing factors of different trajectory groups is crucial. © 2025 Editorial Office of Modern Preventive Medicine. All rights reserved.

关键词： 房屋建筑   装饰装修   环保设计  

摘要： 近些年来,随着我国社会经济的不断发展,社会各界在追求经济发展的同时,也开始逐渐的重视针对于环保问题的研究,再加上目前建筑行业发展的速度非常的快,同时建筑行业和人们的日常生活水平之间有着非常密切的联系,所以这也就对于房屋建筑的装饰装修环保设计提出了更加严格的要求,房屋建筑装饰装修不仅直接影响了人们的日常居住体验,同时也能够影响住户的具体健康.所以在本篇文章当中主要会针对于房屋建筑装饰装修的环保设计问题进行相应的分析,希望能够更好的加强房屋建筑装饰装修的节能发展.

关键词： 读后续写   产出导向法   生成式人工智能   教学设计  

摘要： 作为读写结合的英语学习方法以及高考写作新题型，读后续写要求学生深度联结记叙文阅读输入和写作输出。产出导向法立足驱动、促成和评价三个核心环节，融合语言输入和输出，实现“学用一体”，为有效开展读后续写教学提供了参考路径。本文基于具体案例，通过剖析教学设计和实施过程，阐述教师如何在生成式人工智能辅助下，将产出导向法应用于读后续写教学设计，以提升教学实效。

关键词： 工业厂房   防火设计   应急疏散   安全问题  

摘要： 本文主要研究了工业厂房的防火设计与应急疏散方案.首先介绍了工业厂房火灾的危害性和防火设计的重要性,然后分析了当前存在的问题,提出了相应的解决方法,并给出了结论.

关键词： 装配式高层住宅   超低能耗   建筑节能设计  

摘要： 随着全球气候变化和能源危机的日益严峻,建筑节能减排已成为社会共同关注的重点.为解决传统高层住宅能耗高、资源利用率低的问题,本文首先探讨了装配式高层住宅在节能减排中的潜力,并深入分析了节能设计的理论基础和实施策略.最后结合装配式高层住宅建筑设计实际,提出了相应的建筑节能设计策略,通过上述措施,实现了装配式高层住宅的能耗显著降低和环境性能优化,以此为相关人员提供实践参考.

关键词： Coronary disease   Diabetes mellitus, type 2   Dyslipidemias   Heart function tests   Rosuvastatin calcium  

摘要： Objective To investigate the effects of different doses of rosuvastatin on lipid metabolism and left ventricular function in patients with type 2 diabetes mellitus (T2DM) accompanied by coronary heart disease (CHD). Methods A prospective study was conducted involving 63 patients with T2DM accompanied by CHD who were treated at Jinan 2^nd People's Hospital and The Fifth People's Hospital of Jinan from January 2022 to June 2023. In a randomized case-control study, patients were assigned to either a control group (n = 31, receiving 10 mg/d of rosuvastatin) or an observation group (n = 32, receiving 20 mg/d of rosuvastatin) using a random number table method. After 8 weeks of treatment, the therapeutic effects were evaluated, and blood lipid levels and left ventricular function were recorded before and after treatment. Plasma levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP), homocysteine (Hcy), C-reactive protein (CRP), and the distance covered in a 6-minute walk test were compared between the two groups. Patients were followed for 1 year to monitor adverse reactions and the occurrence of adverse cardiovascular events. Results The effective treatment rate in the observation group was significantly higher than that in the control group [90.63% (29/32) vs. 70.97% (22/31), χ² = 3.95, P < 0.05). Prior to treatment, there were no statistically significant differences between the two groups regarding blood lipid levels, cardiac ultrasound indicators, serum levels of NT-proBNP, Hcy, and CRP, the distance covered in the 6-minute walk test, and the incidences of adverse reactions and adverse cardiovascular events (all P > 0.05). After treatment, both groups showed a reduction in total cholesterol and low-density lipoprotein cholesterol (both P < 0.05), with the observation group demonstrating significantly lower levels (t = 10.54, 14.01, both P < 0.001). Additionally, both groups showed an increase in high-density lipoprotein cholesterol (P < 0.05), but