关键词:
Bio-FET system
extended-gate
MOSFET
pH tests
biofunctionalization
IgG
摘要:
Measuring urine pH and metabolite concentrations is crucial for detecting potential health issues like urinary tract infection, kidney failure, and metabolic disorders. To address this issue, we are working on the development of a Bio-FET system, a biosensor based on field-effect transistors. This system utilizes a microfabricated gold electrode to detect not only urine pH but also specific biomarkers. As a pH sensor, the developed system shows a good response, with a corresponding sensitivity of 2.20 µA/pH. For biomarker detection, the system successfully detected immunoglobulin G, with antigen–antibody binding causing a measurable change of approximately 4 µA.