摘要:
目的
探讨二甲双胍对人增生性瘢痕(HS)成纤维细胞(Fb)增殖及纤维化蛋白表达的影响及其机制。
Objective
To investigate the effects and mechanism of metformin on the proliferation and expression of fibrotic proteins of human hypertrophic scar (HS) fibroblasts (Fbs).
摘要:
目的
探讨人脂肪间充质干细胞(hADMSC)来源细胞外囊泡(EV), 即hADMSC-EV对高糖诱导的人脐静脉内皮细胞(HUVEC)焦亡的影响及其机制, 为改善糖尿病创面中血管功能提供依据。
Objective
To investigate the influence and mechanism of extracellular vesicles (EVs) derived from human adipose-derived mesenchymal stem cells (hADMSCs), i.e. hADMSC-EVs on pyroptosis of human umbilical vein endothelial cells (HUVECs) induced by high glucose, with the aim of providing evidence for improving vascular function in diabetic wounds.