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关键词： 矿物组合   矿化蚀变   成矿流体   钨锡多金属矿床   湘南  

摘要： 采用岩矿鉴定、扫描电镜和电子探针等手段,对湘南地区多个钨锡多金属矿床的矿化蚀变进行了研究和总结。结果表明,湘南地区钨锡多金属矿化蚀变矿物组成复杂,但各矿区普遍存在锡石、黄铜矿、黑钨矿(或白钨矿)、闪锌矿、方铅矿等金属矿物,萤石和黄玉常见,云母化、钾长石化、绿泥石化、尖晶石化等热液蚀变普遍,表明成矿流体具有类似或相同的来源及组分;各矿田(或矿床)的成矿流体均富含B和F等挥发分及Fe和Mn,钨、锡和铜矿化密切共生,钨锡多金属矿石中可见Nb和Be矿化,表明Li、Be、Nb、Ta、W、Sn、Bi、Cu、Pb、Zn等矿化为类似成矿流体的产物;初步研究认为湘南地区的钨锡多金属矿化是同一岩浆房分异演化的成矿流体的产物,提出了成矿的概念模型。

关键词： 湘西   沅麻盆地   古隆起   白垩系   寒武系   古流体   二次生烃   页岩气  

摘要： 因古隆起周缘页岩生烃时间晚、热演化程度低,目前已成为中扬子地区油气勘探的重要领域.雪峰古隆起形成于加里东末期,经历了后期复杂的沉积-构造演化,白垩系覆盖区勘探方向尚未明确.以雪峰古隆起西侧沅麻盆地北部为主要研究对象,通过对不整合于寒武系页岩之上的白垩系底部方解石脉与寒武系页岩方解石脉地球化学和包裹体对比分析,研究了古流体形成环境、来源及其对寒武系生烃演化过程的指示.研究结果表明:(1)白垩系脉体碳氧同位素与围岩具有相似性,REE无明显的Eu异常,与寒武系脉体Eu强正异常对比鲜明,表明白垩系脉体主要来自白垩系,受寒武系页岩的影响弱;(2)白垩系方解石脉采样位置位于构造高位,但是包裹体类型显示以纯水溶液包裹体为主,形成于弱还原-弱氧化的环境,未见沥青和明显的纯甲烷包裹体,表明寒武系大规模生排烃在白垩系沉积之前;(3)以包裹体均一温度和Ro为制约,结合区域地质特征恢复了沅麻盆地寒武系两种类型埋藏史,即沅麻盆地北部草堂凹陷早期深埋藏,白垩纪以来不具二次生烃的条件;辰溪凹陷南部早期浅埋藏,白垩系以来Ro可能由1.2%升至2.5%,二次生烃潜力较大,是下一步勘探的有利区.

关键词： Inflatable-inclined liquid-solid fluidized bed   Fine coal separation   Fluidization   Separation efficiency   Secondary gas velocity   Size fraction  

摘要： To improve the adaptability of fluidized beds for fine coal separation,a new type of liquid-solid fluidized bed was constructed,i.e.,the inflatable-inclined liquid-solid fluidized bed(IILSFB).A combination of simulation analysis and separation experiments was used to analyze the fluidization characteristics and separation performance of the *** results showed that there was upflow and downflow in the fluidized *** upflow was mainly composed of water flow,followed by light and heavy particles;on the other hand,the downflow was caused by the backflow of heavy particles that settled at the inclined *** addition,the light particles that settled at the inclined section could return to the rising water flow under the action of secondary *** the water velocity,separation time,and secondary gas velocity increased,the comprehensive separation efficiency of fine coal in the fluidized bed improved,while the value decreased as the feed quantity *** also indicated the order of importance for these four factors,i.e.,water velocity,separation time,feed quantity,and secondary gas velocity,on ***,the comprehensive separation efficiency of 0.1-1 mm fine coal varied significantly with various factors,while that of∼0.1 mm and 1-3 mm fine coal was always at a low *** the latter case,the classification process of the size fraction was significantly better than the separation process in the fluidized *** optimal working conditions,an IILSFB was used to separate the fine coal(0.1-1 mm).The yield of clean coal was 37.95% with an ash content of 12.11%,and the possible error was 0.085 g/cm^(3),indicating that the IILSFB had good separation performance for 0.1-1 mm fine coal.

关键词： 火驱   燃烧状态   色谱指纹   饱和烃   烯烃   芳香烃   尾气  

摘要： 为认清稠油火驱过程中原油与尾气物理化学性质的变化规律,采用室内三维物理模型开展了稠油火驱实验,并对火驱高温氧化后的原油与尾气开展了饱和烃、芳香烃、烯烃、尾气组分等方面的色谱指纹特征研究。研究表明:稠油火驱后原油物性变好,族组分中饱和烃、芳香烃含量升高;饱和烃色谱指纹图中正构烷烃含量明显增加,轻重比增大;原油中新生成了烯烃化合物,与同碳数饱和烃成对出现且同碳数烯烃与饱和烃比值始终小于0.5;芳香烃色谱指纹图中菲系列化合物发生了明显的甲基转移与脱甲基作用;尾气多维气相色谱图中可见烯烃、氢气、一氧化碳等火驱高温氧化的特征组分。该研究可作为火驱过程中指示燃烧状态的有效技术手段,为稠油火驱燃烧状态的判识提供了支持。

关键词： 地热资源   地热流体   水化学特征   同位素特征   河南  

摘要： 河南省平原地区蕴藏着丰富的地热资源,不同构造单元,不同时代的天然地热流体,其水化学特征及成生环境有较大差异。研究地热流体同位素特征可以了解地热流体来源、年龄、热储温度,同时推断补给、径流和排泄更新周期,对保持地热清洁能源可持续开发利用具有指导意义。通过采用稳定同位素(D、^(18)O)的组成变化判别地热流体的来源或补给源,采用放射性同位素(^(13)C-^(14)C)的衰变规律判断地热流体年龄及补给更新速率,进而得出:地热流体主要来源于大气降水,主要补给区为西部低山丘陵区,平原区地热水年龄在1265 a~39443 a之间,运移速率为2.5 m/a~8 m/a。为河南省地热资源评价提供了数据参考。

关键词： Condensation flow pattern   Convolutional neural network   Machine learning  

摘要： Identifying two-phase flow patterns is fundamental to successfully design and subsequently optimize highprecision heat transfer equipment, given that the heat transfer efficiency and pressure gradients occurring in such thermo-hydraulic systems are dependent on the flow structure of the working fluid. This paper shows that with visualization data and artificial neural networks, the flow pattern images of condensation of R-134a refrigerant in inclined smooth tubes can be classified with more than 98% accuracy. The study considers 10 classes of flow pattern images acquired from previous experimental works for a wide range of flow conditions and the full range of tube inclination angles. Although not the focus of this paper, the use of a Principal Component Analysis allowed feature dimensionality reduction, dataset visualization, and decreased associated computational cost when used together with multilayer perceptron neural networks. In addition, the superior two-dimensional spatial learning capability of convolutional neural networks allowed improved image classification and generalization performance. In both cases, the classification was performed sufficiently fast to enable real-time implementation in two-phase flow systems.

关键词： Aortic Valve Stenosis  

摘要： Introduction There are currently no established prognostic models for low-flow, low-Gradient (LFLG) severe aortic stenosis (AS). The Cardiac Damage Staging Classification, has been validated as a clinically useful prognostic tool in high-gradient severe AS, but not specifically in LFLG severe AS. Objective To assess and confirm the prognostic utility of the Cardiac Damage Staging Classification, in LFLG severe AS patients. Methods We analysed data from the National Echocardiography Database of Australia (NEDA), a national multicentre registry with individual data linkage to mortality. Of 192,060 adults (aged 62.8±17.8 years) with comprehensive ultrasound profiling of the native aortic valve studied between 2000–2019, 12,013 (6.3%) had severe AS. Based on standard echocardiographic parameters, 611 classical and 959 paradoxical LFLG patients were identified. Mean follow-up was 70±41 months. All-cause and cardiovascular-related mortality were assessed for each LFLG group on an adjusted basis (age and sex), according to cardiac damage classification staging. Results Paradoxical LFLG patients were younger (mean age 74.3 vs 76.2, p=0.006) and more often female (62.8% vs 36.3%, p<0.001). Classical LFLG patients had greater associated cardiac damage at diagnosis (76% vs. 49%, for Stage ≥2, p<0.001). Compared to Stage 0 paradoxical LFLG patients, adjusted 1- and 5-year cardiovascular-related mortality was 200% (HR 2.82, 95% CI 1.12–7.11) and 120% (HR 2.42, 95% CI 1.46–4.02) higher in Stage 2 patients and 350% (HR 4.23, 95% CI 1.68–10.63) and 175% (HR 3.18, 95% CI 1.90–5.34) higher in Stage 3/4 patients, respectively. Compared to Stage 1 classical LFLG patients, adjusted 1- and 5-year cardiovascular-related mortality was 58% (HR 1.66, 95% CI 0.95–2.90) and 24% (HR 1.35, 95% CI 0.91–1.99) higher in Stage 2 patients and 125% (HR 2.48, 95% CI 1.43–4.28) and 52% (HR 1.87, 95% CI 1.26–2.78) higher in Stage 3/4 patients, respectively. Conclusion In patients with LFLG severe AS iden

关键词： blind area   PMUTs   ring-down vibration suppress   transfer function  

摘要： In this paper, a novel ring-down suppression system based on transfer function is proposed for the first time to suppress the ring-down time and decrease the blind area of PMUTs (Piezoelectric Micromachined Ultrasonic Transducers). This suppression system includes a transfer function and a simple P (proportion) controller, which can reduce the ring-down time without degrading any performances of PMUTs. The transfer function serves as a virtual PMUT device, feeding its output into the P controller;then, the P controller generates a suppression signal to the actual PMUT device. The ring-down time of a 115-kHz PMUT array is demonstrated to be reduced by up to 93% through the suppression system. In addition, the P controller has been experimentally optimized, reducing the blind area of the PMUT array by about 40%. Moreover, a low ring-down PMUTs system design guideline is established, which is practical and straightforward for industrial scenarios. Finally, the system can be easily integrated into ASIC (Application Specific Integrated Circuit).

关键词： Macroinvertebrate   Indicator species analysis   Functional trait   Hanjiang River Basin   Weihe River Basin  

摘要： The selection of suitable indicators is the key to the development of multi-metric bioassessment. Here, we examined how taxonomic and functional structures of macroinvertebrate communities responded to the environmental gradients in ten mountainous streams in the Weihe River and Hanjiang River basins, two subtropical biodiversity hotspots in central China. Our main objectives were: 1) to examine whether trait-based metrics performed better than taxonomic compositions in differentiating environmental gradients;2) to test whether indicators (species and traits) were more efficient than entire communities in discriminating three site groups subjected to different levels of human disturbances. Our results showed that both taxonomic and functional trait compositions, including species- and trait-based indicators, were all sensitive to environmental disturbance. Particularly, the trait-based variables responded more sensitive to human disturbances. Indicator assemblages can be effective surrogates of entire communities in response to environmental changes. Traits- and indicatorsbased metrics should be considered as useful supplements in the existent bio-monitoring schemes in China. We argued that the combination of taxonomic and functional indicators should be implemented in bioassessment, as they reflect different aspects of environmental changes and anthropogenic disturbances.

关键词： pediatric cancer   pediatric solid tumors   flow cytometry   diagnosis   standardization   immunophenotyping   STOT  

摘要： Early diagnosis of pediatric cancer is key for adequate patient management and improved outcome. Although multiparameter flow cytometry (MFC) has proven of great utility in the diagnosis and classification of hematologic malignancies, its application to non-hematopoietic pediatric tumors remains limited. Here we designed and prospectively validated a new single eight-color antibody combination-solid tumor orientation tube, STOT-for diagnostic screening of pediatric cancer by MFC. A total of 476 samples (139 tumor mass, 138 bone marrow, 86 lymph node, 58 peripheral blood, and 55 other body fluid samples) from 296 patients with diagnostic suspicion of pediatric cancer were analyzed by MFC vs. conventional diagnostic procedures. STOT was designed after several design-test-evaluate-redesign cycles based on a large panel of monoclonal antibody combinations tested on 301 samples. In its final version, STOT consists of a single 8-color/12-marker antibody combination (CD99-CD8/(nu)myogenin/CD4-EpCAM/CD56/GD2/(sm)CD3-CD19/(cy)CD3-CD271/CD45). Prospective validation of STOT in 149 samples showed concordant results with the patient WHO/ICCC-3 diagnosis in 138/149 cases (92.6%). These included: 63/63 (100%) reactive/disease-free samples, 43/44 (98%) malignant and 4/4 (100%) benign non-hematopoietic tumors together with 28/38 (74%) leukemia/lymphoma cases;the only exception was Hodgkin lymphoma that required additional markers to be stained.& nbsp;In addition, STOT allowed accurate discrimination among the four most common subtypes of malignant CD45(-) CD56(++) non-hematopoietic solid tumors: 13/13 (GD2(++) (nu)myogenin(-) CD271(-/+) (nu)MyoD1(-) CD99(-) EpCAM(-)) neuroblastoma samples, 5/5 (GD2(-) (nu)myogenin(++) CD271(++) (nu)MyoD1(++) CD99(-/+) EpCAM(-)) rhabdomyosarcomas, 2/2 (GD2(-/+) (nu)myogenin(-) CD271(+) (nu)MyoD1(-) CD99(+) EpCAM(-)) Ewing sarcoma family of tumors, and 7/7 (GD2(-) (nu)myogenin(-) CD271(+) (nu)MyoD1(-) CD99(-) EpCAM(+)) Wilms tumors. In summary, here