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摘要： Squamous cell carcinoma of the colon is a rare tumor and primary cecal localization is unusual. This malignant condition is marked by a worst prognosis due to early local invasion. We report a case of a 46-year-old female patient admitted to the emergency department with symptoms of peritonitis. CT scan showed a cecal tumor perforated in the retroperitoneal space. The patient underwent right hemicolectomy with D2 lymphadenectomy without intestinal anastomosis. The diagnosis of squamous cell carcinoma was confirmed by histopathological examination. Squamous cell carcinoma is a malignant tumor with poor prognosis, hence, the interest of early diagnosis and management.

关键词： 方案设计   建筑设计   功能分区  

摘要： 方案设计是建筑设计中的重要环节,对后续施工起到很大的制约作用,直接影响建筑工程质量.方案设计体现了科学设计的特征,有利于把握整体设计效果和实现造价管控.本文从优化总平面设计、优化功能区划分、优化建筑细节部分等几个方面对方案设计的应用策略进行了研究和探讨.

关键词： Sobolev equation   Finite difference   Local meshless method   RBF   LRBF-PUM   Error estimate  

摘要： This paper develops a numerical approach for finding the approximate solution of the Sobolev model. This model describes many natural processes, such as thermal conduction for different media and fluid evolution in soils and rocks. The proposed method approximates the unknown solution with the help of two main stages. At a first stage, the time discretization is performed by means of a second-order finite difference procedure. At a second stage, the space discretization is accomplished using the local radial basis function partition of unity collocation method based on the finite difference (LRBF-PUM-FD). The major disadvantage of global techniques is the high computational burden of solving large linear systems. The LRBF-PUM-FD significantly sparsifies the linear system and reduces the computational burden, while simultaneously maintaining a high accuracy level. The time-discrete formulation is studied in terms of the stability and convergence analysis via the energy method. Three examples are illustrated to verify the efficiency and accuracy of the method. (C) 2021 Elsevier Inc. All rights reserved.

关键词： 道路桥梁   伸缩缝施工设计   质量控制  

摘要： 道路桥梁是我国交通事业快速发展的保障.施工技术水平的不断提升,不仅提升了施工效率,也有效提高了施工质量.在实际工程施工中,伸缩缝施工技术是道路桥梁施工中的重要构成部分.本文从设计与质量控制角度对此项技术进行了相应分析,望能够给相关工作者带来一定的启示.

摘要：

Roy Taylor and colleagues explain how type 2 diabetes can be reversed by weight loss and avoidance of weight regain

关键词： shrimp allergy   tropomyosin   Lit v 1   T-cell epitope   B-cell epitope  

摘要： Development of efficient peptide-based immunotherapy for shrimp allergy relies on the identification of the dominant T-cell epitopes of its major allergen, tropomyosin. In this study, immunoinformatic tools, T-cell proliferation, cytokine release, IgG/ IgE binding, and degranulation assays were used to identify and characterize the T-cell epitopes in Lit v 1 in comparison with previously validated B-cell epitopes. The results showed that of the six in silico predicted T-cell epitopes only one (T2: VQESLLKANIQLVEK, 60-74) promoted T-cell proliferation, the release of IL-2, and upregulated secretion of Th2-associated cytokines in the absence of IgG/IgE binding and degranulation activities. These findings support T2 as a candidate for the development of an efficient peptide-based vaccine for the immunotherapy for shrimp-allergic patients.

关键词： Phosphoric acid fuel cell   Organic Rankine cycle   CCHP   Exergy efficiency   Thermal energy storage tank   Current density  

摘要： In recent years, combined generation systems have become more popular due to their advantages such as high overall efficiency, low fuel consumption, low emissions and lower operating costs. Using fuel cell as prime mover with high efficiency and low pollution can be a solution to achieve higher efficiencies in the combined generation systems. In this study, performance of a novel combined cooling, heating and power system or trigeneration system with phosphoric acid fuel cell along with an organic Rankine cycle is conducted. The system includes a hydrogen storage tank, a phosphoric acid fuel cell, an afterburner, an organic Rankine cycle, a thermal energy storage tank, an absorption chiller, and heat exchangers. For recovery of the waste heat of phosphoric acid fuel cell, three heat recovery systems (the organic Rankine cycle, absorption chiller and, domestic hot water system) are proposed to meet the electricity, cooling and heating needs of a building. The use of heat storage tank and absorption chiller to use the waste heat of the fuel cell and utilize of organic Rankine cycle to supply some part of the power, in a new arrangement is one of the most important novelties of this study. The impacts of current density, operating pressure, and operating temperature of fuel cell on the performance of the trigeneration system are investigated from the perspectives of energy and exergy. The net electrical power of the trigeneration system is 432.8 kW, the cooling capacity is 17.5 kW, and the heating capacity is 90.7 kW, and the domestic hot water capacity is 128.5 kW. The results show increment of 57% in energy efficiency and 5.3% in exergy efficiency of the trigeneration system compared to the phosphoric acid fuel cell lonely. Also, with increasing the current density and operating temperature, energy and exergy efficiencies of the trigeneration system decrease, while increasing the operating pressure leads to rise of these parameters. Additionally, irreversibility of t

关键词： Architectural coated woven fabrics   PES/PVC fabrics   mechanical properties   tensile stiffness parameters   biaxial test  

摘要： Down to the present day, the determination of stiffness parameters for architectural fabrics, mainly used as coated woven fabrics, is a field of intense discussion. Designers and material producers are affected by an existing uncertainty. The present contribution investigates the possibility to provide tables of tensile stiffness parameters for specific materials in which tensile stiffness values are given dependent on the material's tensile strength. The focus is on PVC-coated polyester fabrics as the most commonly used material for textile architecture. Materials of four different producers have been tested experimentally. Furthermore, from each material producer products of different strength classes have been considered in the test series. To achieve a general statement on the possibility of material classification according to their tensile stiffness, material parameters of two different material formulations have been investigated: (1) for a simplified but widely applied linear-elastic material model based on a standardized test and evaluation method and (2) for a recently developed more advanced orthotropic hyperelastic nonlinear material model. The tensile stiffness parameters are statistically evaluated and compared. In order to achieve a required basis, standardized and project-specific biaxial test procedures are presented and analysed in combination with established evaluation procedures. A tabulation of tensile stiffness parameters would be of great help for design engineers and material producers. The results of the present work will lead to a possible classified tabulation of the investigated materials in a meaningful manner.