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关键词： 光栅设计   光学设计   严格耦合波分析   超表面   微结构设计  

摘要： 通过对傅里叶模态法（Fourier Modal Method），也称严格的耦合波分析算法（Rigorous Coupled Wave Analysis）的攻关与研究，文章介绍了一款国产的光栅设计与分析软件——光栅设计者，该软件独立开发，并达到了完全自主可控，旨在填补国内光栅光学设计分析软件的空白。软件从算法开发与攻关开始，目前已取得了重大进展并即将发布。软件全部核心代码自主率达到100%，与Virtual Lab和Gsolver等国际主流光栅设计软件的计算精度相当，且提供了更多的光栅类型设计与分析支持，涵盖了一维、二维光栅与微结构和超表面等复杂光学结构。光栅设计者以简明的界面，表格化的参数输入，灵活多变的光栅结构建模，强大的参数扫描能力和高效的并行效率为特点，降低了用户的学习成本，能够适应从极紫外到太赫兹波段的电磁场计算与分析。

关键词： Red-peeled   Citrus   Carotenoid   beta-citraurin   Carotenoid cleavage dioxygenase 4b1 ( CCD4b1 )   Phytoene synthase 1 (PSY1)  

摘要： Peel color in citrus is largely genetically controlled. Red peel is favored by customers and is important, therefore, for fruit external quality. In order to understand the factors affecting distribution of carotenoids and color intensity of red -peeled citrus, we compared carotenoid accumulation and gene expression in the peel of twelve fully ripe red -peeled citrus cultivars with different genetic backgrounds. The results showed that 8-citraurin, a red C 30 carotenoid, was the second or third most abundant colored carotenoid in the peel of all twelve red -peeled citrus, ranging from 9.4 % to 26.7 % of total carotenoids. Statistical analysis of carotenoid composition and content showed that of the main carotenoids 8-citraurin had the highest correlation with red appearance of cultivars. In addition, 8-cryptoxanthin, which accounted for 3.6 % to 16.4 % of the total carotenoids, were also significantly positively correlated with citrus color index (CCI). The expression of two key genes, phytoene synthase 1 ( PSY1 ) and carotenoid cleavage dioxygenase 4b1 ( CCD4b1 ), differed among cultivars with a range of 3.5and 48.8 -fold, respectively. Surprisingly, accumulation of total carotenoids and 8-citraurin was not correlated with the expression of PSY1 and CCD4b1 , respectively, implying that diverse factors influence high carotenoid accumulation in red -peeled citrus.

关键词： Sorafenib   HMSNs   RSM-CCD   Drug delivery   Anti-cancer activity  

摘要： Hollow mesoporous silica nanoparticles (HMSNs) are considered appealing nanovehicles for drug delivery due to their exceptional drug loading and release potential. This study plans to synthesize HMSNs using a novel, quick, and economical procedure in co-relation with traditional mesoporous silica nanoparticles (MSNs) and optimize their synthesis by using the RSM-CCD approach. The influence of independent variables, i.e., CTAB (X1), TEOS (X2), and pH (X3), was evaluated by a 3 -factorial design and ANOVA. RSM-CCD depicted the best synthesis formulation. CTAB: 0.3 g, TEOS: 3 ml, pH: 11.5. Optimized MSNs and HMSNs were characterized by DLS, XRD, SEM, FTIR, TEM, BET, XPS, and FE-SEM. Subsequently, hemocompatibility analysis revealed excellent compatibility of the nanosamples toward human RBCs. The drug loading efficiency of SF-MSNs and SF-HMSNs was 13.71 +/- 0.33 % and 51.31 +/- 0.94 %, respectively. A drug dissolution study revealed that sorafenib (SF) was released sustainably, with a cumulative release percentage of 67 % (HMSNs) and 77 % (MSNs) at 72 h, proving the superiority of SF-HMSNs over sustained release. In-vitro cell culture studies explored the anti-tumorigenic prospects of free and encapsulated SF. Cell cytotoxicity was assessed by MTT assay against A549 cells, indicating enhanced toxicity for optimized SF-HMSNs. The IC50 value substantially decreased from 10.5 to 5.8 mu g/ml (a 1.8-fold decrease) after encapsulation. Additionally, In-vitro assays reflected MMP-mediated apoptotic cell death in A549 cells due to increased drug sensitivity and ROS generation. Collectively, these findings suggest that HMSNs are an ideal drug delivery vehicle due to the sustainable release of SF for NSCLC treatment.

关键词： Photocatalysis   Activated carbon   Wastewater   Biomass conversion   Pharmaceutical contaminations  

摘要： Mitigating pharmaceutical pollution in the global environment is imperative, and tetracycline (TC) is a commonly utilized antibiotic in human and veterinary medicine. The persistent existence of TC highlights the necessity of establishing efficient measures to protect water systems and the environment from detrimental contaminants. Herein, a novel rhubarb seed waste-derived activated carbon-supported photocatalyst (WO3-ZnO/ RUAC) was synthesized by combining wet impregnation and ultrasonic methods. The activated carbon (AC) was obtained from rhubarb seed waste for the first time via chemical activation. The function of AC as an electron acceptor and in separating electron-hole pairs was illuminated by characterization analyses that included XRD, FTIR, XPS, SEM, TEM, PL, EIS, TPC, and UV-DRS. Using the response surface methodology-central composite design (RSM-CCD) technique, the synthesis parameters of the composite were systematically optimized. Under ideal conditions, with a TC concentration of 33 mg. L-1, pH of 4.57, irradiation time of 108 min, and catalyst dose of 0.85 g. L-1, the highest degradation efficiency of TC by this composite, achieved 96.5%, and it was reusable for five cycles. Subsequently, trapping tests and electron spin resonance (ESR) analysis were conducted, elucidating that center dot OH and center dot O2- radicals played pivotal roles in the photocatalytic degradation of TC. This research offers valuable insights into utilizing the AC-based photocatalyst to degrade pharmaceutical micropollutants effectively.

关键词： 光子晶体光纤   表面等离子体共振   折射率传感器  

摘要： 为了实现对待测介质折射率的高灵敏度检测,设计并研究了一种基于表面等离子体共振技术的光子晶体光纤折射率传感器.该传感器的内外空气孔呈正六边形排列,在包层外壁上涂覆银-石墨烯纳米薄膜,通过纤芯基模和表面等离子体模的耦合程度来检测周围环境的折射率变化.研究表明,该传感器可以实现折射率在1.37～1.38范围内的检测,最高灵敏度可达40000nm/RIU,分辨率可达4.17×10-5RIU.

关键词： 智慧交通   毫米波雷达   视觉传感器   时空融合  

摘要： 针对单传感器检测的不足和复杂的道路环境,本文设计了视觉传感器与毫米波雷达的车辆目标检测融合算法.通过传感器的参数标定与坐标转换构建了空间融合模型,首先获取了传感器的内参及实际安装的位置信息,然后将毫米波雷达的坐标变换到图像的像素坐标,实现了传感器的时间融合.实验结果表明,与单一传感器的检测结果相比,视觉传感器与毫米波雷达的融合算法能够显著改善视频杂波、雷达的多点分布以及检测目标的分割等问题,目标检测的准确率高于单一传感器,特别是在复杂场景中,融合算法检测的稳定性更高.

关键词： 放射治疗   塑料闪烁体光纤剂量计   蒙特卡罗模拟   空间分辨率  

摘要： 针对放射治疗过程中，需精准控制癌细胞受照靶区照射剂量的问题，设计了一种塑料闪烁体光纤剂量计，可实现在线实时剂量测量的同时，还具有耐辐照、可远距离测量等优点，在X射线放射治疗中具有明显优势。首先借助已标定的端窗出射式微型X射线管对研制的塑料闪烁体光纤剂量计进行标定，其次利用蒙特卡罗模拟软件MCNP进行模拟仿真，然后借助SUN NUCLEAR corporation组织等效片对塑料闪烁体光纤剂量计的空间分辨率展开研究，仿真实验与实验测量结果表明该剂量计具有较高的三维空间分辨率，其横向空间剂量分布符合高斯分布，相关系数均在0.99以上；纵向空间剂量分布符合指数衰减规律，相关系数均大于0.98。

关键词： Charge coupled devices  

摘要： We present a refined equivalent pinhole model (REPM) for 3D reconstruction from spaceborne linear-array charge-coupled device (CCD) imagery. The rational functional model (RFM) is the mainstream model for linear-array CCD satellite cameras, however, it has some limitations. Notably, the RFM has no rigorous physical interpretation and differs significantly from the pinhole camera model (PCM), hence, it cannot be directly applied to existing 3D reconstruction approaches in computer vision. Meanwhile, existing perspective camera approximation model (PCAM) has the problem of reprojection error, which cannot be directly applied to the 3D reconstruction calculation of large-scale image. Therefore, we induce the reprojection error of the PCAM, which indicates that the error is determined by the image size and the height range of the interesing area. Based on the error analysis, we firstly propose an image partition module to crop the large-scale images to several small parts for further computation. We further generate virtual grid points of the interesting area both horizontally and vertically to reproject the cropped images to minimize the reprojection error. Thus, a novel pipeline for 3D reconstruction named REPM is proposed. We conducted the experiments on different images covering various areas from different linear-array CCD sensors to verify the proposed approach. The results indicate that our pipeline has higher accuracy and completeness and exhibits the great potential. Our image partition module enables the 3D reconstruction pipeline to process large-scale images, and our image geometric correction model enhances the accuracy and completeness of the 3D reconstruction, especially for large-scale images. The implementation of the pipeline is available at https://***/2022hong/REPMSatelliteStereo. © 2024, The Authors. All rights reserved.

关键词： 7075铝合金   激光重熔   表面织构   覆盖率   摩擦学性能  

摘要： 为了提高7075铝合金的耐磨性能。采用不同扫描速度在铝合金表面进行激光重熔处理，分析了重熔区的组织和纳米硬度，研究重熔处理对7075铝合金表面力学性能的影响，以及不同织构覆盖率对7075铝合金表面的磨损行为，并分析了微光栅织构对重熔表面的磨损机理。激光重熔处理对7075铝合金组织和力学性能均有影响，与未重熔的基体相比，激光重熔区的硬度得到明显提升，当扫描速度增加到900 mm/s时，重熔区的硬度高达1957.9 MPa，硬度提高了约88.8%；激光重熔表面处理对铝合金的抗拉强度影响不大、其织构方向对伸长率影响明显；随着织构覆盖率的增加，在水润滑条件下的平均摩擦系数和磨损量都呈现出先减小后增大的趋势，其中20%织构覆盖率比未重熔的试样摩擦系数降低了约16.7%，而磨损量降低了约48.8%。微光栅织构构筑起的硬-软交替“三明治”结构可以有效抑制大而深的剥落形成，它为氧化磨屑在摩擦界面的集聚提供了容纳空间，从而有效降低了摩擦副材料的去除，并促使磨损机制由磨粒磨损和疲劳磨损的双重损伤转变为以轻微疲劳剥落特征为代表的疲劳磨损，进一步提高了7075铝合金的耐磨性能。