新型冠状病毒肺炎——专题资源库

COVID-19 causes more delay in managed care launch for Illinois youth

《Mental Health Weekly》  2020年 第12期30卷

The state of Illinois is further delaying the transition to a managed care health coverage system for children in the custody of the Department of Children and Family Services (DCFS), this time citing the COVID-19 outbreak as the reason for delay, the Southern Illinoisan reported March 16. “Recognizing the unprecedented challenges families, medical providers, and state agencies are facing from COVID-19, the launch of YouthCare services for DCFS youth in care will be postponed a minimum of 30...

The state of Illinois is further delaying the transition to a managed care health coverage system for children in the custody of the Department of Children and Family Services (DCFS), this time citing the COVID-19 outbreak as the reason for delay, the Southern Illinoisan reported March 16. “Recognizing the unprecedented challenges families, medical providers, and state agencies are facing from COVID-19, the launch of YouthCare services for DCFS youth in care will be postponed a minimum of 30 days,” the Illinois Department of Healthcare and Family Services said in a statement. Most Medicaid recipients in Illinois are already under a managed care system, known as IlliniCare. Under that system, the state pays a flat, monthly per-patient fee to private insurance companies to manage the care of Medicaid patients. The state has been planning for some time to shift foster children and other minors in the custody of DCFS into a managed care system, YouthCare, but that transition was delayed several times. Those delays have mostly been out of concern that there won't be a large enough network of participating health care providers that can serve the unique physical, mental and behavioral health needs of that population. And so, for now, they remain in a traditional fee-for-service coverage plan, DHFS and DCFS officials stated.

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新型冠状病毒肺炎诊疗方案(试行第五版 修正版)

《中国中西医结合杂志》  2020年 第2期40卷 136-138页

2019年12月以来,湖北省武汉市陆续发现了多例新型冠状病毒肺炎患者,随着疫情的蔓延,我国其他地区及境外也相继发现了此类病例。该病作为急性呼吸道传染病已纳入《中华人民共和国传染病防治法》规定的乙类传染病,按甲类传染病管理。随着疾病认识的深入和诊疗经验的积累,国家卫生健康委及国家中医药管理局对《新型冠状病毒感染的肺炎诊疗方案(试行第五版)》进行修正,形成了《新型冠状病毒肺炎诊疗方案(试行第五版修正版)》。

2019年12月以来,湖北省武汉市陆续发现了多例新型冠状病毒肺炎患者,随着疫情的蔓延,我国其他地区及境外也相继发现了此类病例。该病作为急性呼吸道传染病已纳入《中华人民共和国传染病防治法》规定的乙类传染病,按甲类传染病管理。随着疾病认识的深入和诊疗经验的积累,国家卫生健康委及国家中医药管理局对《新型冠状病毒感染的肺炎诊疗方案(试行第五版)》进行修正,形成了《新型冠状病毒肺炎诊疗方案(试行第五版修正版)》。

关键词： 冠状病毒感染   甲类传染病   诊疗方案   肺炎患者   急性呼吸道传染病   诊疗经验   卫生健康   第五版  

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中西医结合治疗新型冠状病毒肺炎重症患者的思考

董国菊 王冰 李浩 

《中国中西医结合杂志》  2020年 第3期40卷 269-271页

2019年12月以来,湖北省武汉市陆续发现不明原因的肺炎,陆续在全国各地均出现受感染病例[1],并且在武汉市、湖北省乃至全国引起暴发性流行,甚至引发世界多国如韩国、日本、意大利、伊朗的大流行。2020年2月11日,世界卫生组织总干事谭德塞在瑞士日内瓦宣布,将此次肺炎命名为新型冠状病毒肺炎(corona virus disease 2019,COVID-19)。该病具有传染性极强、潜伏期长、临床表现多样、易感人群广等特点[2]。

2019年12月以来,湖北省武汉市陆续发现不明原因的肺炎,陆续在全国各地均出现受感染病例[1],并且在武汉市、湖北省乃至全国引起暴发性流行,甚至引发世界多国如韩国、日本、意大利、伊朗的大流行。2020年2月11日,世界卫生组织总干事谭德塞在瑞士日内瓦宣布,将此次肺炎命名为新型冠状病毒肺炎(corona virus disease 2019,COVID-19)。该病具有传染性极强、潜伏期长、临床表现多样、易感人群广等特点[2]。

关键词： 瑞士日内瓦   肺炎   易感人群   不明原因   感染病例   传染性  

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Mass gathering events and reducing further global spread of COVID-19: a political and public health dilemma

McCloskey, Brian Zumla, Alimuddin Ippolito, Giuseppe Blumberg, Lucille Arbon, Paul Cicero, Anita Endericks, Tina Lim, Poh Lian Borodina, Maya 

《LANCET》  2020年 第10230期395卷 1096-1099页

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从戾气学说谈新型冠状病毒肺炎的中医诊治

张馨月 郑佳昆 

《河南中医》  2020年 第3期40卷 336-338页

新型冠状病毒,传染性强,人感染后出现的症状相似,且病情变化迅速,病死率较高,与中医学所述之戾气相似。从此次戾气致病的临床表现来看,为寒湿疫,侵犯人体途径为侵卫犯肺,直犯营血,逆传心包,邪气也可直趋中道,伏于膜原。病情传变可由表入里,又窜走六经、三焦。新型冠状病毒肺炎是一种急性感染性肺炎,在疾病发展不同时期,表现症状略有不同。早期病机为湿毒郁肺,枢机不利,宜化湿解毒、宣肺行气,方选藿朴夏苓汤合三仁汤、小柴胡汤加减;中期病机为热毒闭肺,腑气不通,宜清热宣肺、通腑泻热,方选麻杏石甘汤合黄连解毒汤加减;极期病机为内闭外脱...

新型冠状病毒,传染性强,人感染后出现的症状相似,且病情变化迅速,病死率较高,与中医学所述之戾气相似。从此次戾气致病的临床表现来看,为寒湿疫,侵犯人体途径为侵卫犯肺,直犯营血,逆传心包,邪气也可直趋中道,伏于膜原。病情传变可由表入里,又窜走六经、三焦。新型冠状病毒肺炎是一种急性感染性肺炎,在疾病发展不同时期,表现症状略有不同。早期病机为湿毒郁肺,枢机不利,宜化湿解毒、宣肺行气,方选藿朴夏苓汤合三仁汤、小柴胡汤加减;中期病机为热毒闭肺,腑气不通,宜清热宣肺、通腑泻热,方选麻杏石甘汤合黄连解毒汤加减;极期病机为内闭外脱,宜开闭固脱、清热救逆,方选四逆汤合安宫牛黄丸、紫雪丹加减;恢复期病机为气阴两虚,肺脾两虚,余邪未尽,宜益气养阴,补脾肺,祛余热邪毒,方用二陈汤合参苓白术散、王氏清暑益气汤加减。在预防方面,应提高人体自身免疫力,可用玉屏风散加味益气固表。

关键词： 新型冠状病毒   新型冠状病毒肺炎   戾气   寒湿疫  

来源： 维普期刊服务平台

新冠肺炎疫情对全球生产体系的冲击和我国产业链加速外移的风险分析

祝坤福 高翔 杨翠红 汪寿阳 

《中国科学院院刊》  2020年 第3期35卷 283-288页

新冠肺炎疫情短期内严重冲击了我国生产供应,加大了国内产业链加速外移的风险。文章基于当前疫情导致我国短期生产与出口供给缺口的研究,结合我国在全球生产网络和亚洲生产链的枢纽位置,就疫情对全球产业链的冲击及其引发的我国产业链加速外移风险进行了剖析。研究结果表明,疫情引起的产能缺口将对全球生产体系产生冲击,跨国企业将加快生产链布局调整,需密切关注疫情造成部分产业链加速外移的风险。最后,就企业复工保障、疫情防控和产业链布局等方面提出相关政策建议。

新冠肺炎疫情短期内严重冲击了我国生产供应,加大了国内产业链加速外移的风险。文章基于当前疫情导致我国短期生产与出口供给缺口的研究,结合我国在全球生产网络和亚洲生产链的枢纽位置,就疫情对全球产业链的冲击及其引发的我国产业链加速外移风险进行了剖析。研究结果表明,疫情引起的产能缺口将对全球生产体系产生冲击,跨国企业将加快生产链布局调整,需密切关注疫情造成部分产业链加速外移的风险。最后,就企业复工保障、疫情防控和产业链布局等方面提出相关政策建议。

关键词： 新冠肺炎   产能缺口   全球生产网络   产业链外移  

来源： 国家哲学社会科学学术...

Mental health care for international Chinese students affected by the COVID-19 outbreak

Yusen Zhai Xue Du 

《The lancet. Psychiatry》  2020年 第4期7卷 e22页

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Transmission potential of the novel coronavirus (COVID-19) onboard the diamond Princess Cruises Ship, 2020

Kenji Mizumoto Gerardo Chowell 

《Infectious Disease Modelling》  2020年 第1期5卷 264-270页

An outbreak of COVID-19 developed aboard the Princess Cruises Ship during January eFebruary *** mathematical modeling and time-series incidence data describing the trajectory of the outbreak among passengers and crew members,we characterize how the transmission potential varied over the course of the *** estimate of the mean reproduction number in the confined setting reached values as high as^11,which is higher than mean estimates reported from community-level transmission dynamics in China ...

An outbreak of COVID-19 developed aboard the Princess Cruises Ship during January eFebruary *** mathematical modeling and time-series incidence data describing the trajectory of the outbreak among passengers and crew members,we characterize how the transmission potential varied over the course of the *** estimate of the mean reproduction number in the confined setting reached values as high as^11,which is higher than mean estimates reported from community-level transmission dynamics in China and Singapore(approximate range:1.1e7).Our findings suggest that Rt decreased substantially compared to values during the early phase after the Japanese government implemented an enhanced quarantine *** recent estimates of Rt reached values largely below the epidemic threshold,indicating that a secondary outbreak of the novel coronavirus was unlikely to occur aboard the Diamond Princess Ship.

关键词： Corona   Epidemic   Confined settings   Cruise   Next generation matrix  

来源： PubMed ScienceDirect Journa... MEDLINE期刊

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study (vol 395, pg 1054, 2020)

Zhou, F. Yu, T. Du, R. 

《LANCET》  2020年 第10229期395卷 1038-1038页

Summary Background Since December, 2019, Wuhan, China, has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological and clinical characteristics of patients with COVID-19 have been reported but risk factors for mortality and a detailed clinical course of illness, including viral shedding, have not been well *** In this retrospective, multicentre cohort study, we included all adult inpatients (≥...

Summary Background Since December, 2019, Wuhan, China, has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological and clinical characteristics of patients with COVID-19 have been reported but risk factors for mortality and a detailed clinical course of illness, including viral shedding, have not been well *** In this retrospective, multicentre cohort study, we included all adult inpatients (≥18 years old) with laboratory-confirmed COVID-19 from Jinyintan Hospital and Wuhan Pulmonary Hospital (Wuhan, China) who had been discharged or had died by Jan 31, 2020. Demographic, clinical, treatment, and laboratory data, including serial samples for viral RNA detection, were extracted from electronic medical records and compared between survivors and non-survivors. We used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital *** 191 patients (135 from Jinyintan Hospital and 56 from Wuhan Pulmonary Hospital) were included in this study, of whom 137 were discharged and 54 died in hospital. 91 (48%) patients had a comorbidity, with hypertension being the most common (58 [30%] patients), followed by diabetes (36 [19%] patients) and coronary heart disease (15 [8%] patients). Multivariable regression showed increasing odds of in-hospital death associated with older age (odds ratio 1·10, 95% CI 1·03-1·17, per year increase; p=0·0043), higher Sequential Organ Failure Assessment (SOFA) score (5·65, 2·61-12·23; p<0·0001), and d-dimer greater than 1 μg/mL (18·42, 2·64-128·55; p=0·0033) on admission. Median duration of viral shedding was 20·0 days (IQR 17·0-24·0) in survivors, but SARS-CoV-2 was detectable until death in non-survivors. The longest observed duration of viral shedding in survivors was 37 *** The potential risk factors of older age, high SOFA score, and d-dimer greater than

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武汉一线耳鼻咽喉头颈外科医护人员应对新型冠状病毒的现状和建议

张亚 杨修平 李双 肖伟 刘萌芷 徐晓翔 苏红果 吴婷婷 宋鹏 陈雄 

《临床耳鼻咽喉头颈外科杂志》  2020年 第3期34卷 193-195页

随着武汉抗击疫情的不断深入,新型冠状病毒(SARS-CoV-2)的防控工作进入了关键时期。战斗在一线的医务人员是这场战役的英雄,耳鼻咽喉头颈外科医护也是一支不可忽视的力量,同样发挥了重要作用。耳鼻喉科门诊量大,多数疾病与上呼吸道有关,症状不典型或者以咽喉为首发症状的新冠肺炎患者有分流到耳鼻喉科的潜在风险。本文主要分析和探讨耳鼻咽喉头颈外科在新冠肺炎诊疗中的作用以及抗击疫情一线的耳鼻咽喉头颈外科医护人员的身心健康状况。

随着武汉抗击疫情的不断深入,新型冠状病毒(SARS-CoV-2)的防控工作进入了关键时期。战斗在一线的医务人员是这场战役的英雄,耳鼻咽喉头颈外科医护也是一支不可忽视的力量,同样发挥了重要作用。耳鼻喉科门诊量大,多数疾病与上呼吸道有关,症状不典型或者以咽喉为首发症状的新冠肺炎患者有分流到耳鼻喉科的潜在风险。本文主要分析和探讨耳鼻咽喉头颈外科在新冠肺炎诊疗中的作用以及抗击疫情一线的耳鼻咽喉头颈外科医护人员的身心健康状况。

关键词： 新型冠状病毒   病毒性肺炎   医务防护   建议  

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Policies on the use of respiratory protection for hospital health workers to protect from coronavirus disease (COVID-19)

Chughtai, Abrar A. Seale, Holly Islam, Md Saiful Owais, Mohammad Macintyre, C. Raina 

《INTERNATIONAL JOURNAL OF NURSING STUDIES》  2020年 105卷 103567-000页

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Evidence informing the UK's COVID-19 public health response must be transparent

Alwan, Nisreen A. Bhopal, Raj Burgess, Rochelle A. Colbourn, Tim Cuevas, Luis E. Smith, George Davey Egger, Matthias Eldridge, Sandra Gallo, Valentina Gilthorpe, Mark S. Greenhalgh, Trish Griffiths, Christopher Hunter, Paul R. Jaffar, Shabbar Jepson, Ruth Low, Nicola Martineau, Adrian McCoy, David Orcutt, Miriam Pankhania, Bharat Pikhart, Hynek Pollock, Allyson Scally, Gabriel Smith, James Sridhar, Devi Taylor, Stephanie Tennant, Peter W. G. Themistocleous, Yrene Wilson, Anne 

《LANCET》  2020年 第10229期395卷 1036-+页

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Health security capacities in the context of COVID-19 outbreak: an analysis of International Health Regulations annual report data from 182 countries

Kandel, Nirmal Chungong, Stella Omaar, Abbas Xing, Jun 

《LANCET》  2020年 第10229期395卷 1047-1053页

Background Public health measures to prevent, detect, and respond to events are essential to control public health risks, including infectious disease outbreaks, as highlighted in the International Health Regulations (IHR). In light of the outbreak of 2019 novel coronavirus disease (COVID-19), we aimed to review existing health security capacities against public health risks and events. Methods We used 18 indicators from the IHR State Party Annual Reporting (SPAR) tool and associated data fro...

Background Public health measures to prevent, detect, and respond to events are essential to control public health risks, including infectious disease outbreaks, as highlighted in the International Health Regulations (IHR). In light of the outbreak of 2019 novel coronavirus disease (COVID-19), we aimed to review existing health security capacities against public health risks and events. Methods We used 18 indicators from the IHR State Party Annual Reporting (SPAR) tool and associated data from national SPAR reports to develop five indices: (1) prevent, (2) detect, (3) respond, (4) enabling function, and (5) operational readiness. We used SPAR 2018 data for all of the indicators and categorised countries into five levels across the indices, in which level 1 indicated the lowest level of national capacity and level 5 the highest. We also analysed data at the regional level (using the six geographical WHO regions). Findings Of 182 countries, 52 (28%) had prevent capacities at levels 1 or 2, and 60 (33%) had response capacities at levels 1 or 2. 81 (45%) countries had prevent capacities and 78 (43%) had response capacities at levels 4 or 5, indicating that these countries were operationally ready. 138 (76%) countries scored more highly in the detect index than in the other indices. 44 (24%) countries did not have an effective enabling function for public health risks and events, including infectious disease outbreaks (7 [4%] at level 1 and 37 [ 20%] at level 2). 102 (56%) countries had level 4 or level 5 enabling function capacities in place. 32 (18%) countries had low readiness (2 [1%] at level 1 and 30 [17%] at level 2), and 104 (57%) countries were operationally ready to prevent, detect, and control an outbreak of a novel infectious disease (66 [36%] at level 4 and 38 [21%] at level 5). Interpretation Countries vary widely in terms of their capacity to prevent, detect, and respond to outbreaks. Half of all countries analysed have strong operational readiness capaciti

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从2019-nCoV和SARS-CoV的侵袭靶点血管紧张素转化酶2寻找新型冠状病毒肺炎的救治策略

唐子健 李树仁 许文华 申泽雪 

《中国全科医学》  2020年 第9期23卷 1071-1077页

自2019年12月以来,新型冠状病毒(2019-nCoV)感染在中国武汉引发了新型冠状病毒肺炎的爆发,并引起了公众的极大关注。2019-nCoV与SARS-CoV均属于冠状病毒科,均通过血管紧张素转化酶2(ACE2)侵入靶细胞。深入了解ACE2及病毒侵入人体后以其为中心引起的一系列病生理变化机制,可能有助于发现并解释相应的临床现象,进而及时予以处理;另外ACE2是潜在的治疗靶点,可以此寻找相应的救治策略。本文阐述了ACE2在2019-nCoV及SARS-CoV所致多脏器损伤中的作用、针对ACE2的靶向阻断药物以及抑制炎性反应的药物,旨在为后续相关研究及诊治、药物研发提供依据。

自2019年12月以来,新型冠状病毒(2019-nCoV)感染在中国武汉引发了新型冠状病毒肺炎的爆发,并引起了公众的极大关注。2019-nCoV与SARS-CoV均属于冠状病毒科,均通过血管紧张素转化酶2(ACE2)侵入靶细胞。深入了解ACE2及病毒侵入人体后以其为中心引起的一系列病生理变化机制,可能有助于发现并解释相应的临床现象,进而及时予以处理;另外ACE2是潜在的治疗靶点,可以此寻找相应的救治策略。本文阐述了ACE2在2019-nCoV及SARS-CoV所致多脏器损伤中的作用、针对ACE2的靶向阻断药物以及抑制炎性反应的药物,旨在为后续相关研究及诊治、药物研发提供依据。

关键词： 冠状病毒感染   新型冠状病毒   SARS冠状病毒   血管紧张素转化酶2  

来源： 维普期刊服务平台