新型冠状病毒肺炎——专题资源库

新型冠状病毒肺炎疫期肿瘤患者防控的挑战与对策

王卫东 冯梅 郎锦义 

《肿瘤预防与治疗》  2020年 第2期33卷 87-90页

由于手术、放化疗等手段对机体免疫功能造成伤害,肿瘤患者对新型冠状病毒(Severe Acute Respiratory Syndrome Coronavirus 2,SARS-CoV-2)具有更高的易感性,病情更加凶险,预后极差。肿瘤临床表现的多样性,增加了疑似病例的筛查难度,使得肿瘤患者防控面临诸多挑战。鉴于此,分类管理、精准施策,免疫功能重建,优化肿瘤诊疗路径,以及对特殊场所的精细化防护将是当前肿瘤特殊人群的有效防控策略。

由于手术、放化疗等手段对机体免疫功能造成伤害,肿瘤患者对新型冠状病毒(Severe Acute Respiratory Syndrome Coronavirus 2,SARS-CoV-2)具有更高的易感性,病情更加凶险,预后极差。肿瘤临床表现的多样性,增加了疑似病例的筛查难度,使得肿瘤患者防控面临诸多挑战。鉴于此,分类管理、精准施策,免疫功能重建,优化肿瘤诊疗路径,以及对特殊场所的精细化防护将是当前肿瘤特殊人群的有效防控策略。

关键词： 肿瘤   新冠病毒   防控   对策  

来源：

肿瘤专科医院分区分类精准防控新型冠状病毒肺炎疫情实践

吴建林 乔良 刘潇霞 赵宇倩 郎锦义 

《肿瘤预防与治疗》  2020年 第2期33卷 91-93页

新型冠状病毒肺炎疫情期间,针对恶性肿瘤患者易感性高、预后不佳、死亡风险较高,但治疗不可间断的特殊情况,提出肿瘤专科医院采取分区分类精准防控对策,有效指导全院科学、规范、有序、有效开展防控,严防院内疫情发生和传播。

新型冠状病毒肺炎疫情期间,针对恶性肿瘤患者易感性高、预后不佳、死亡风险较高,但治疗不可间断的特殊情况,提出肿瘤专科医院采取分区分类精准防控对策,有效指导全院科学、规范、有序、有效开展防控,严防院内疫情发生和传播。

关键词： 新冠肺炎   肿瘤   分区防控   实践  

来源：

新型冠状病毒肺炎疫期肿瘤患者的心理应激及防护对策

张玉萍 罗稀 张健 江宾 江庆华 

《肿瘤预防与治疗》  2020年 第2期33卷 106-110页

抗肿瘤治疗对机体免疫功能的损害会导致肿瘤患者对新型冠状病毒(Severe Acute Respiratory Syndrome Coronavirus 2,SARS-CoV-2)具有更高的易感性,且预后极差。新型冠状病毒肺炎疫情期间,患者的日常生活节律和治疗计划被扰乱。疫情和病情让患者感受到极大的生命安全威胁,共同构成了叠加性压力,给患者带来的严重的心身危害。因此,应当建立以患者自助防护为中心的全方位多层级心理服务模式,以提高患者的应对能力,减轻心理应激反应。本文总结并分析了肿瘤患者在SARS-CoV-2疫情期间的心理应激反应特点和发生机制,并提出了以患者自助防护为中...

抗肿瘤治疗对机体免疫功能的损害会导致肿瘤患者对新型冠状病毒(Severe Acute Respiratory Syndrome Coronavirus 2,SARS-CoV-2)具有更高的易感性,且预后极差。新型冠状病毒肺炎疫情期间,患者的日常生活节律和治疗计划被扰乱。疫情和病情让患者感受到极大的生命安全威胁,共同构成了叠加性压力,给患者带来的严重的心身危害。因此,应当建立以患者自助防护为中心的全方位多层级心理服务模式,以提高患者的应对能力,减轻心理应激反应。本文总结并分析了肿瘤患者在SARS-CoV-2疫情期间的心理应激反应特点和发生机制,并提出了以患者自助防护为中心的三级心理防护对策,以期为加强危机管理,完善疫情期间肿瘤患者心理应激干预及管理对策奠定基础。

关键词： 肿瘤   新型冠状病毒   心理应激   防护   对策  

来源：

新型冠状病毒肺炎疫情期间接受抗肿瘤治疗患者的药学监护

胡志强 马雪 漆婷婷 蒋刚 肖洪涛 蒋倩 程凯 

《肿瘤预防与治疗》  2020年 第2期33卷 100-105页

目的:探讨新型冠状病毒肺炎(Corona Virus Disease 2019,COVID-19)疫情期间,如何科学有效地降低接受抗肿瘤治疗的癌症患者被感染的风险。方法:从临床药师和循证医学角度,通过查阅文献、指南,梳理肿瘤患者在COVID-19疫情期间的用药监护点。结果:疫情期间肿瘤患者是COVID-19的易感人群,但目前尚无针对性的预防药物。专业人员应引导肿瘤患者正确预防COVID-19,以加强营养、提高自身免疫力为主。同时,可根据指南积极预防与抗肿瘤治疗相关的感染,一旦出现发热等与COVID-19相似的症状时,就应注意与抗肿瘤药物的不良反应鉴别。结论:疫情期间抗肿...

目的:探讨新型冠状病毒肺炎(Corona Virus Disease 2019,COVID-19)疫情期间,如何科学有效地降低接受抗肿瘤治疗的癌症患者被感染的风险。方法:从临床药师和循证医学角度,通过查阅文献、指南,梳理肿瘤患者在COVID-19疫情期间的用药监护点。结果:疫情期间肿瘤患者是COVID-19的易感人群,但目前尚无针对性的预防药物。专业人员应引导肿瘤患者正确预防COVID-19,以加强营养、提高自身免疫力为主。同时,可根据指南积极预防与抗肿瘤治疗相关的感染,一旦出现发热等与COVID-19相似的症状时,就应注意与抗肿瘤药物的不良反应鉴别。结论:疫情期间抗肿瘤治疗的药学监护专业性强,需多学科合作并不断完善。临床药师可参考本文对疫情期间抗肿瘤治疗的药学监护建议,协助医护人员,指导肿瘤患者科学应对疫情。

关键词： 新型冠状病毒肺炎   抗肿瘤治疗   药学监护   循证医学  

来源：

新型冠状病毒感染的肺炎防控知识问答

李俊华 高立冬 

湖南科学技术出版社  2020

全书聚焦广大人民群众关注的焦点，采用问答的形式，从疾病基础知识、病例发现与治疗、个人预防知识、公共预防知识、消毒、重点场所防控知识等六个部分，引领公众正确认识新型冠状病毒及其感染所致的临床表现、传播途径、易感人群，并采取规范有效的防护措施，同时，对一些高风险场所如何开展防控给出了专业、可操作性强的指导，旨在拨开笼罩在公众头上疑云，扫清因不明真相而产生的不必要的恐慌和误解，从而科学认识疾病、积极防范疾病。本书内容规范，图文并茂，深入浅出，力求为广大人民群众和有关单位提供及时、权威的防疫指导。

ISBN: (纸本)9787535799043

全书聚焦广大人民群众关注的焦点，采用问答的形式，从疾病基础知识、病例发现与治疗、个人预防知识、公共预防知识、消毒、重点场所防控知识等六个部分，引领公众正确认识新型冠状病毒及其感染所致的临床表现、传播途径、易感人群，并采取规范有效的防护措施，同时，对一些高风险场所如何开展防控给出了专业、可操作性强的指导，旨在拨开笼罩在公众头上疑云，扫清因不明真相而产生的不必要的恐慌和误解，从而科学认识疾病、积极防范疾病。本书内容规范，图文并茂，深入浅出，力求为广大人民群众和有关单位提供及时、权威的防疫指导。

关键词： 新型冠状病毒-新冠肺炎-肺炎-流行病  

来源： 重庆大学图书馆图书

新型冠状病毒感染的肺炎防控知识120

山东省疾病预防控制中心编 

山东人民出版社  2020

本书针对群众对于新型冠状病毒感染的肺炎有关热点，从新型冠状病毒的特点、感染的临床表现与救治、个人和社区预防措施、心理干预等方面进行了解答，并对常见的认识误区进行了纠正。

ISBN: (纸本)9787209126076

本书针对群众对于新型冠状病毒感染的肺炎有关热点，从新型冠状病毒的特点、感染的临床表现与救治、个人和社区预防措施、心理干预等方面进行了解答，并对常见的认识误区进行了纠正。

关键词： 日冕形病毒  

来源： 重庆大学图书馆图书

Coronavirus disease 2019 (COVID-19): update for anesthesiologists and intensivists March 2020

Thomas-Rueddel, D. Winning, J. Dickmann, P. Ouart, D. Kortgen, A. Janssens, U. Bauer, M. 

《ANAESTHESIST》  2020年 第4期69卷 225-235页

The current outbreak of coronavirus disease (COVID-19) has reached Germany. The majority of people infected present with mild disease, but there are severe cases that need intensive care. Unlike other acute infectious diseases progressing to sepsis, the severe courses of COVID19 seemingly show prolonged progression from onset of first symptoms to life-threatening deterioration of (primarily) lung function. Diagnosis relies on PCR using specimens from the respiratory tract. Severe ARDS reflect...

The current outbreak of coronavirus disease (COVID-19) has reached Germany. The majority of people infected present with mild disease, but there are severe cases that need intensive care. Unlike other acute infectious diseases progressing to sepsis, the severe courses of COVID19 seemingly show prolonged progression from onset of first symptoms to life-threatening deterioration of (primarily) lung function. Diagnosis relies on PCR using specimens from the respiratory tract. Severe ARDS reflects the hallmark of a critical course of the disease. Preventing nosocomial infections (primarily by correct use of personal protective equipment) and maintenance of hospitals' operational capability are of utmost importance. Departments of Anaesthesia, Intensive Care and emergency medicine will envisage major challenges.

关键词： Infectious disease outbreaks   Infection control   Emergency medicine   Anesthesiology   Intensive care  

来源：

Clinical features of pediatric patients with COVID-19: a report of two family cluster cases

Li-Na Ji Shuang Chao Yue-Jiao Wang Xue-Jun Li Xiang-Dong Mu Ming-Gui Lin Rong-Meng Jiang 

《World Journal of Pediatrics》  2020年 第3期16卷 267-270页

Background Coronovirus disease 2019 (COVID-19) has spread rapidly across the *** of all ages are susceptible to ***,literature reports on pediatric patients are *** To improve the recognition of COVID-19 infection in children,we retrospectively reviewed two confirmed pediatric cases from two family *** clinical features and laboratory examination results of the children and their family members were *** The two confirmed children only presented with mild respiratory or gastrointestinal *** of...

Background Coronovirus disease 2019 (COVID-19) has spread rapidly across the *** of all ages are susceptible to ***,literature reports on pediatric patients are *** To improve the recognition of COVID-19 infection in children,we retrospectively reviewed two confirmed pediatric cases from two family *** clinical features and laboratory examination results of the children and their family members were *** The two confirmed children only presented with mild respiratory or gastrointestinal *** of them had normal chest CT *** general and symptomatic treatments,both children recovered *** families had travel histories to Hubei *** Pediatric patients with COVID-19 are mostly owing to family cluster or with a close contact *** children have relatively milder clinical symptoms than infected *** should attach importance to early recognition,early diagnosis,and early treatment of infected children.

关键词： Children   Coronavirus   COVID-19   Wuhan  

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Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19

Calisher, Charles Carroll, Dennis Colwell, Rita Corley, Ronald B. Daszak, Peter Drosten, Christian Enjuanes, Luis Farrar, Jere My Field, Hume Golding, Josie Gorbalenya, Alexander Haagmans, Bart Hughes, James M. Karesh, William B. Keusch, Gerald T. Lam, Sai Kit Lubroth, Juan Mackenzie, John S. Madoff, Larry Mazet, Jonna Palese, Peter Perlman, Stanley Poon, Leo Roizman, Bernard Sail, Linda Subbarao, Kanta Turner, Mike 

《LANCET》  2020年 第10226期395卷 E42-E43页

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Recommendations for critically ill patients with COVID-19

Kluge, Stefan Janssens, Uwe Welte, Tobias Weber-Carstens, Steffen Marx, Gernot Karagiannidis, Christian 

《MEDIZINISCHE KLINIK-INTENSIVMEDIZIN UND NOTFALLMEDIZIN》  2020年 第3期115卷 175-177页

Since December 2019, a novel coronavirus (severe acute respiratory syndrome-coronavirus 2, SARS-CoV-2) has rapidly spread around the world resulting in an acute respiratory illness pandemic. The majority of patients presents with mild symptoms of coronavirus disease 2019 (COVID-19). However, about 5% become critically ill and require intensive care treatment. Acute hypoxemic failure with severe dyspnea and an increased respiratory rate (>30/min) usually leads to ICU admission. At that point, ...

Since December 2019, a novel coronavirus (severe acute respiratory syndrome-coronavirus 2, SARS-CoV-2) has rapidly spread around the world resulting in an acute respiratory illness pandemic. The majority of patients presents with mild symptoms of coronavirus disease 2019 (COVID-19). However, about 5% become critically ill and require intensive care treatment. Acute hypoxemic failure with severe dyspnea and an increased respiratory rate (>30/min) usually leads to ICU admission. At that point, bilateral pulmonary infiltrates are typically seen. Patients often develop a severe acute respiratory distress syndrome (ARDS). To date there is no specific treatment available-the main goal of supportive therapy is to ascertain adequate oxygenation. Early intubation and repeated prone positioning are key elements in treating hypoxemic COVID-19 patients. Strict adherence to basic infection control measures (including hand hygiene) and use of personal protection equipment (PPE) are essential in the care of patients. Procedures that lead to formation of aerosols should be avoided where possible and carried out with utmost precaution.

关键词： COVID-19   Coronavirus   Acute respiratory failure   ARDS   High-flow Nasal Cannula  

来源：

COVID-19: too little, too late?

[Anonymous] 

《LANCET》  2020年 第10226期395卷 755-755页

来源：

Are high-performing health systems resilient against the COVID-19 epidemic?

Legido-Quigley, Helena Asgari, Nima Teo, Yik Ying Leung, Gabriel M. Oshitani, Hitoshi Fukuda, Keiji Cook, Alex R. Hsu, Li Yang Shibuya, Kenji Heymann, David 

《LANCET》  2020年 第10227期395卷 848-850页

[...]intragovernmental coordination was improved because health authorities drew on their experiences of severe acute respiratory syndrome during 2002–03 in Hong Kong and Singapore, H5N1 avian influenza in 1997 in Hong Kong, and the 2009 influenza H1N1 pandemic in all three locations.[...]all locations adapted financing measures so that all direct costs for treating patients are borne by the governments.[...]the trust of patients, health-care professionals, and society as a whole in governme...

[...]intragovernmental coordination was improved because health authorities drew on their experiences of severe acute respiratory syndrome during 2002–03 in Hong Kong and Singapore, H5N1 avian influenza in 1997 in Hong Kong, and the 2009 influenza H1N1 pandemic in all three locations.[...]all locations adapted financing measures so that all direct costs for treating patients are borne by the governments.[...]the trust of patients, health-care professionals, and society as a whole in government is of paramount importance for meeting health crises.

关键词：

来源：

COVID-19: fighting panic with information

The Lancet 

《Lancet (London, England)》  2020年 第10224期395卷 537页

来源：

Coronavirus COVID-19 impacts to dentistry and potential salivary diagnosis

Sabino-Silva, Robinson Jardim, Ana Carolina Gomes Siqueira, Walter L. 

《CLINICAL ORAL INVESTIGATIONS》  2020年 第4期24卷 1619-1621页

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