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防疫指南

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2020

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Critical care crisis and some recommendations during the COVID-19 epidemic in China: Xie, Jianfeng Tong, Zhaohui Guan, Xiangdong Du, Bin Qiu, Haibo Slutsky, Arthur S.; 《INTENSIVE CARE MEDICINE》 2020年第5期46卷 837-840页; Since December 2019, a severe acute respiratory infection (SARI) caused by 2019 novel coronavirus (SARS-CoV-2), began to spread from Wuhan to all of China [1, 2], and indeed the world. As of Feb 10, 2020, there are more than 40,000 confirmed cases and > 1000 deaths in China.; Since December 2019, a severe acute respiratory infection (SARI) caused by 2019 novel coronavirus (SARS-CoV-2), began to spread from Wuhan to all of China [1, 2], and indeed the world. As of Feb 10, 2020, there are more than 40,000 confirmed cases and > 1000 deaths in China.; 关键词：; 来源：

Brain Awareness Week, CoVID-19 infection and Neurological Sciences: Federico, Antonio; 《NEUROLOGICAL SCIENCES》 2020年第4期41卷 747-748页; Brain Awareness Week is the global campaign to foster public enthusiasm and support for brain science. Every March, “partners host imaginative activities in their communities that share the wonders of the brain and the impact brain science has on our everyday lives”.; Brain Awareness Week is the global campaign to foster public enthusiasm and support for brain science. Every March, “partners host imaginative activities in their communities that share the wonders of the brain and the impact brain science has on our everyday lives”.; 关键词：; 来源：

Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs: LUO Hui TANG Qiao-ling SHANG Ya-xi LIANG Shi-bing YANG Ming Nicola Robinson LIU Jian-ping; 《Chinese Journal of Integrative Medicine》 2020年第4期26卷 243-250页; Objective:Since December 2019,an outbreak of corona virus disease 2019(COVID-19)occurred in Wuhan,and rapidly spread to almost all parts of *** was followed by prevention programs recommending Chinese medicine(CM)for the *** order to provide evidenee for CM recommendations,we reviewed ancient classics and human ***:Historical records on prevention and treatment of infections in CM classics,clinical evidence of CM on the prevention of severe acute respiratory syndrome(SARS)and H1N1 in flue nza...; Objective:Since December 2019,an outbreak of corona virus disease 2019(COVID-19)occurred in Wuhan,and rapidly spread to almost all parts of *** was followed by prevention programs recommending Chinese medicine(CM)for the *** order to provide evidenee for CM recommendations,we reviewed ancient classics and human ***:Historical records on prevention and treatment of infections in CM classics,clinical evidence of CM on the prevention of severe acute respiratory syndrome(SARS)and H1N1 in flue nza,and CM preve ntion programs issued by health authorities in China since the COVID-19 outbreak were retrieved from differe nt databases and websites till 12 February,*** evide nee in eluded data from clinical trials,cohort or other population studies using CM for preventing contagious respiratory virus ***:The use of CM to prevent epidemics of infectious diseases was traced back to ancient Chinese practice cited in Huangdi's Internal Classic(Huang Di Nei Jing)where preventive effects were *** were 3 studies using CM for prevention of SARS and 4 studies for H1N1 *** of the participants who took CM contracted SARS in the 3 *** infection rate of H1N1 in flue nza in the CM group was significantly lower than the non-CM group(relative risk 0.36,95%confidence interval 0.24-0.52;n=4).For prevention of COVID-19,23 provinces in China issued CM *** main principles of CM use were to tonify qi to protect from external pathoge ns,disperse wind and discharge heat,and resolve damp *** most frequently used herbs in eluded Radix astragali(Huangqi),Radix glycyrrhizae(Gancao),Radix saposhnikoviae(Fangfeng),Rhizoma Atractylodis Macrocephalae(Baizhu),Lonicerae Japonicae Flos(Jinyinhua),and Fructus forsythia(Lianqiao).Conclusions:Based on historical records and human evidenee of SARS and H1N1 influenza prevention,Chinese herbal formula could be an alternative approach for prevention of COVID-19 in high-risk; 关键词： Chinese medicine corona virus disease 2019(COVID-19) prevention program clinical evidence review; 来源：

Imaging changes of severe COVID-19 pneumonia in advanced stage: Zhang, Wei; 《INTENSIVE CARE MEDICINE》 2020年第5期46卷 841-843页; We recently reported in Intensive Care Medicine the imaging changes of acute stage from a case of 75-year-old male patient with severe COVID-19 pneumonia combined acute respiratory distress syndrome (ARDS), septic shock, and multiple organ disfunction syndrome (MODS) who had a history of 10-year hypertension and 1-year diabetes. He presently received advanced life support treatment including respiratory support (invasive mechanical ventilation) and circulatory support (vasoconstrictor assista...; We recently reported in Intensive Care Medicine the imaging changes of acute stage from a case of 75-year-old male patient with severe COVID-19 pneumonia combined acute respiratory distress syndrome (ARDS), septic shock, and multiple organ disfunction syndrome (MODS) who had a history of 10-year hypertension and 1-year diabetes. He presently received advanced life support treatment including respiratory support (invasive mechanical ventilation) and circulatory support (vasoconstrictor assistance), as well as intermittent renal replacement therapy (IRRT) in intensive care unit (ICU) of our hospital—a tertiary teaching hospital of medical university. Because his MODS still existed on the day 20 after symptom onset, we had to re-examine the chest computed tomographic (CT). The results showed that early changes of reticular pulmonary fibrosis appeared in Panels D, E, and F (marked by green arrows), compensatory emphysema occurred in Panels D and E (marked by blue arrows), and pulmonary cavity formation appeared in Panel F (marked by blue arrows), compared with acute stage of the day 5 after symptom onset, inflammatory lesions and ground glass shadow of Panels A and B (marked by red arrows), as well as septal line of Panel C (marked by yellow arrows). Presently, this patient is still under the condition of advanced life support therapy (Fig. 1).; 关键词：; 来源：

COVID-19 control in China during mass population movements at New Year: Chen, Simiao Yang, Juntao Yang, Weizhong Wang, Chen Barnighausen, Till; 《LANCET》 2020年第10226期395卷 764-766页; [...]of these policies and public information and education campaigns, Chinese citizens started to take measures to protect themselves against COVID-19, such as staying at home as far as possible, limiting social contacts, and wearing protective masks when they needed to move in public.[...]the Chinese Government encouraged and supported grassroots activities for routine screening, contact tracing, and early detection and medical care of COVID-19 patients, and it promoted hand washing, surfac...; [...]of these policies and public information and education campaigns, Chinese citizens started to take measures to protect themselves against COVID-19, such as staying at home as far as possible, limiting social contacts, and wearing protective masks when they needed to move in public.[...]the Chinese Government encouraged and supported grassroots activities for routine screening, contact tracing, and early detection and medical care of COVID-19 patients, and it promoted hand washing, surface disinfection, and the use of protective masks through social marketing and media.[...]governments should tailor the design of such outbreak-control closure periods to the specific epidemic characteristics of the novel disease, such as the incubation period and transmission routes.; 关键词：; 来源：

Imaging changes in severe COVID-19 pneumonia: Zhang, Wei; 《INTENSIVE CARE MEDICINE》 2020年第4期46卷 583-585页; A 75-year-old male who was confirmed as suffering of severe COVID pneumonia was transferred to the intensive care unit (ICU) of our hospital—a tertiary teaching hospital of a medical university. He had a history of 10-year hypertension and one-year diabetes. A physical examination unveiled that his body temperature was 35.5 ℃, his pulse was 54 beats per minute, his blood pressure was 136/79 mm Hg (noradrenaline 0.2 µg/kg/min), his oxygen saturation was 91% (noninvasive ventilation), and ox...; A 75-year-old male who was confirmed as suffering of severe COVID pneumonia was transferred to the intensive care unit (ICU) of our hospital—a tertiary teaching hospital of a medical university. He had a history of 10-year hypertension and one-year diabetes. A physical examination unveiled that his body temperature was 35.5 ℃, his pulse was 54 beats per minute, his blood pressure was 136/79 mm Hg (noradrenaline 0.2 µg/kg/min), his oxygen saturation was 91% (noninvasive ventilation), and oxygenation index (OI: PO2/FiO2) 100 mmHg. He was diagnosed with severe COVID-19 pneumonia combined with acute respiratory distress syndrome (ARDS), septic shock, and multiple organ dysfunction syndrome (MODS). We focused on the typical imaging feature of chest CT in the patient (Fig. 1). The white “Septal Line” marked by the red arrow in Fig. 1 (Panel a-d) suggests that cellulosic exudation occurred in the surface of lung lobes. In dynamic imaging, these white lines are clearly visible, which provides evidence for us to judge severe COVID-19 pneumonia. In the three-dimensional imaging system, three-dimensional reconstruction of bilateral lung lesions provided a key clue for early identification of the disease. Presently, his condition is relatively stable.; 关键词：; 来源：

What are the risks of COVID-19 infection in pregnant women?: Qiao, Jie; 《LANCET》 2020年第10226期395卷 760-762页; Since December, 2019, the outbreak of the 2019 novel coronavirus disease (COVID-19) infection has become a major epidemic threat in China.Soe Zeya Tun/Reuters Previous studies have shown that SARS during pregnancy is associated with a high incidence of adverse maternal and neonatal complications, such as spontaneous miscarriage, preterm delivery, intrauterine growth restriction, application of endotracheal intubation, admission to the intensive care unit, renal failure, and disseminated intra...; Since December, 2019, the outbreak of the 2019 novel coronavirus disease (COVID-19) infection has become a major epidemic threat in China.Soe Zeya Tun/Reuters Previous studies have shown that SARS during pregnancy is associated with a high incidence of adverse maternal and neonatal complications, such as spontaneous miscarriage, preterm delivery, intrauterine growth restriction, application of endotracheal intubation, admission to the intensive care unit, renal failure, and disseminated intravascular coagulopathy.9,11 However, pregnant women with COVID-19 infection in the present study had fewer adverse maternal and neonatal complications and outcomes than would be anticipated for those with SARS-CoV-1 infection.[...]pregnant women and newborn babies should be considered key at-risk populations in strategies focusing on prevention and management of COVID-19 infection.; 关键词：; 来源：

Safety and efficacy of different anesthetic regimens for parturients with COVID-19 undergoing Cesarean delivery: a case series of 17 patients: Chen, Rong Zhang, Yuan Huang, Lei Cheng, Bi-heng Xia, Zhong-yuan Meng, Qing-tao; 《CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE》 2020年第6期67卷 655-663页; Purpose To assess the management and safety of epidural or general anesthesia for Cesarean delivery in parturients with coronavirus disease (COVID-19) and their newborns, and to evaluate the standardized procedures for protecting medical staff. Methods We retrospectively reviewed the cases of parturients diagnosed with severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection disease (COVID-19). Their epidemiologic history, chest computed tomography scans, laboratory measurements, ...; Purpose To assess the management and safety of epidural or general anesthesia for Cesarean delivery in parturients with coronavirus disease (COVID-19) and their newborns, and to evaluate the standardized procedures for protecting medical staff. Methods We retrospectively reviewed the cases of parturients diagnosed with severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection disease (COVID-19). Their epidemiologic history, chest computed tomography scans, laboratory measurements, and SARS-CoV-2 nucleic acid positivity were evaluated. We also recorded the patients' demographic and clinical characteristics, anesthesia and surgery-related data, maternal and neonatal complications, as well as the health status of the involved medical staff. Results The clinical characteristics of 17 pregnant women infected with SARS-CoV-2 were similar to those previously reported in non-pregnant adult patients. All of the 17 patients underwent Cesarean delivery with anesthesia performed according to standardized anesthesia/surgery procedures. Fourteen of the patients underwent continuous epidural anesthesia with 12 experiencing significant intraoperative hypotension. Three patients received general anesthesia with tracheal intubation because emergency surgery was needed. Three of the parturients are still recovering from their Cesarean delivery and are receiving in-hospital treatment for COVID-19. Three neonates were born prematurely. There were no deaths or serious neonatal asphyxia events. All neonatal SARS-CoV-2 nucleic acid tests were negative. No medical staff were infected throughout the patient care period. Conclusions Both epidural and general anesthesia were safely used for Cesarean delivery in the parturients with COVID-19. Nevertheless, the incidence of hypotension during epidural anesthesia appeared excessive. Proper patient transfer, medical staff access procedures, and effective biosafety precautions are important to protect medical staff from COVID-19.; 关键词：; 来源：

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